UnusualCryptosporidiumGenotypes in Human Cases of Diarrhea

Abstract

Several Cryptosporidium spp. are known to infect humans, but most cases of illness are caused by Cryptosporidium hominis or C. parvum . During a long-term genotyping in the United Kingdom, we identified 3 unusual Cryptosporidium genotypes (skunk, horse, and rabbit) in human patients with diarrhea.

An Epidemiological Study on Endoparasites of Domestic Rabbits (Oryctolagus cuniculus) in Egypt with Special Reference to Their Health Impact

“…Although the first report of rabbit Cryptosporidium was noticed in 1912 (Tyzzer 1912), the concerns regarding Cryptosporidium infection in rabbits have only occurred in recent years due to a few sporadic human cases and a serious waterborne outbreak of cryptosporidiosis caused by Cryptosporidium cuniculus (previously named as Cryptosporidium rabbit genotype) (Chalmers et al 2009;Molloy et al 2010;Robinson et al 2008).…”

Long-term Cryptosporidium typing reveals the aetiology and species-specific epidemiology of human cryptosporidiosis in England and Wales, 2000 to 2003

“…Although these are the most commonly found species in human cryptosporidiosis worldwide, the distribution varies temporally and geographically [1]. Six other Cryptosporidium species have also been found in this host (Cryptosporidium meleagridis, Cryptosporidium felis, Cryptosporidium canis, Cryptosporidium suis, Cryptosporidium muris and Cryptosporidium andersoni), as have C. hominis monkey genotype, C. parvum mouse genotype and the Cryptosporidium cervine, chipmunk genotype I, skunk, horse and rabbit genotypes [4,5,6]. The site-specific occurrence and pathogenicity of these unusual Cryptosporidium species/genotypes in humans appears to depend on a combination of endemnicity, exposure and parasiterelated factors rather than host immune status [7].…”

Ocorrência de Cryptosporidium spp. em animais exóticos de companhia no Brasil

“…Todas essas espécies já foram descritas em humanos e apresentam importância em saúde pública. Como C. cuniculus foi descoberto recentemente como um importante agente etiológico de enfermidade clínica em humanos (Robinson et al, 2008;Molloy et al, 2010), e há raros estudos relacionados a esse parasito, em estudos futuros seria importante classificar os isolados de coelhos em nível de espécie, e não somente de gênero.…”