Unusual Occurrence of Tongue Sensorial Disorder after Conservative Surgical Treatment of Lymphoepithelial Cyst

Sousa, Luane Macêdo de; Albuquerque, Assis Felipe Medeiros; Silva, Paulo Goberlânio de Barros; Bezerra, Thâmara Manoela Marinho; Luna, Ealber Carvalho Macedo; Chaves, Filipe Nobre; Carvalho, Francisco Samuel Rodrigues; Alves, Ana Paula Negreiros Nunes; Ribeiro, Thyciana Rodrigues; Costa, Fábio Wildson Gurgel

doi:10.1155/2015/352463

Cited by 3 publications

(7 citation statements)

References 23 publications

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“…The 26 LEC cases presented herein represent less than 0.1% of all biopsies accessioned in a single oral pathology laboratory during a 37-year period, while in two previous studies they respective figures were 0.11% in 53 years ( 2 ) and 0.1% in 40 years ( 1 ). The asymptomatic nature of LECs that make their recognition mostly an incidental finding ( 3 , 9 , 19 , 39 , 49 ), as well as their clinical misdiagnosis as normal anatomic structures, e.g. foliate papillae ( 53 ) may account for the rarity of recorded cases.…”

Section: Discussionmentioning

confidence: 99%

Oral lymphoepithelial cyst: A clinicopathological study of 26 cases and review of the literature

et al. 2017

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IntroductionΤo describe the clinicopathological features of 26 oral lymphoepithelial cysts (LECs) and review the literature.Material and MethodsTwenty-six cases of oral LECs diagnosed during a 37-year period were retrospectively collected. The patients’ gender and age, as well as the main clinical features of the cysts were retrieved from the requisition forms. The main microscopic features were recorded after reevaluation of all cases. Pubmed and Google Scholar electronic databases were searched with the key word “oral LEC”. Inclusion criteria were the microscopic confirmation of LEC diagnosis and the report at least two of three main clinical features (gender, age and cyst’s location).ResultsThe 26 oral LECs represented 0.08% of 31,564 biopsies accessioned during the study period. They affected 25 patients, 14 females and 11 males with a mean age of 33.04±9.81 years. They appeared as smooth (92%) nodules, with soft (24%) or firm (76%) consistency and normal (28%), yellow to normal (20%), yellow (32%) or white (20%) hue, in the tongue (69.23%) or the floor of mouth (30.77%). They were covered by parakeratinized squamous (92.31%) or non-keratinized (7.69%) epithelium and contained desquamated epithelial cells, amorphous eosinophilic material and/or inflammatory cells (100%). The lymphoid tissue surrounded the cystic cavity partially (34.62%) or completely (65.38%), often in a follicular pattern with prominent germinal centers (53.85%). Literature review yielded 316 cases of oral LECs derived from 25 case reports, 3 case studies/retrospective studies with detailed information for each case and 7 studies with summarized data.ConclusionsOral LEC is a pathologic entity with discrete clinical presentation that is, however, commonly misdiagnosed in clinical practice as other, mostly benign, entities. Its pathogenesis remains obscure, as its clinicopathologic features are consistent with both theories suggested up to date. Key words:Oral lymphoepithelial cyst; developmental cyst; non odontogenic cyst; lymphoid tissue; oral tonsil.

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Section: Discussionmentioning

confidence: 99%

Oral lymphoepithelial cyst: A clinicopathological study of 26 cases and review of the literature

et al. 2017

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“…The connective tissue wall is usually formed of diffuse lymphoid tissue with frequently observed germinal centers. Our case showed all of these features [12]. …”

Section: Discussionmentioning

confidence: 82%

“…Few cases were also reported in soft and hard palate, retromolar area, palatoglossal arch, and palatine tonsil [12, 16, 17]. …”

Section: Discussionmentioning

confidence: 99%

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Nonneoplastic Tongue Swellings of Lymphatic and Lymphocytic Origin: Three Case Reports

Aziz

Yussif

2016

Case Reports in Dentistry

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Tongue is formed of a mass of muscles and salivary gland embedded in anterior highly vascular and posterior lymphoid stroma and covered by specialized surface epithelium. Growths from all of these heterogonous components may occur resulting in a wide variation in clinical features and behavior, ranging from self-limiting to aggressive lesions. Therefore, surgical excision is the treatment of choice. The aim of the current study is to report three different lesions that came to the Oral Surgery Department in the Faculty of Oral and Dental Medicine, Cairo University. Following clinical and histopathological examination, the diagnosis of reactive lymphoproliferative lesion, cystic lymphoepithelial lesion, and developmental lymphatic vessel malformation was reached.

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A Retrospective Clinico-Pathological Analysis with Review of Literature of Oral and Cervical Lympho-Epithelial Cysts from a Pathological Perspective

et al. 2022

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Oral and cervical lympho-epthelial cysts (LECs) are uncommon lesions with histopathological similarities. The aim of the study is to present clinico-pathological characteristics of oral and cervical LECs with a review of literature in order to create awareness on this uncommon entity. Eighteen new cases of oral and cervical LECs obtained from the archives of the University of Peradeniya and University of Geneva were used for the clinico-pathological analysis. The average age at diagnosis of 7 oral and 11 cervical LECs were 40 and 36 years, respectively. Both showed a female predilection (male:female ratio at 3:4 and 4:7, respectively). The only difference was found in the size of the lesions with oral LECs being significantly smaller than cervical LECs (0.9 cm vs. 4.6 cm). LECs may clinically resemble neoplasms (4/18), including malignancies (1/11 in the present series). None of the 18 LECs recurred following surgical removal. The literature-review-based analysis of 514 oral LECs confirms that the lesions are observed predominantly in adults in 4th–5th decades of life and are relatively small lesions of less than 2 cm in diameter. Oral LECs were found to occur predominantly in the tongue and floor of the mouth, similar to 88% of lesions in literature. In conclusion, oral and cervical LECs are two histologically similar cysts that occur in two distinct sites. The literature review supports the information observed in our study with respect to age of occurrence, site predilections, and size. Cervical LECs, particularly the ones that occur in the parotid region, may require further investigations to exclude BLEL of parotid gland, which occur in HIV infected patients.

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Unusual Occurrence of Tongue Sensorial Disorder after Conservative Surgical Treatment of Lymphoepithelial Cyst

Cited by 3 publications

References 23 publications

Oral lymphoepithelial cyst: A clinicopathological study of 26 cases and review of the literature

Oral lymphoepithelial cyst: A clinicopathological study of 26 cases and review of the literature

Nonneoplastic Tongue Swellings of Lymphatic and Lymphocytic Origin: Three Case Reports

A Retrospective Clinico-Pathological Analysis with Review of Literature of Oral and Cervical Lympho-Epithelial Cysts from a Pathological Perspective

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