Unusual presentation of an uncommon lung malignancy

Abstract

Combined type of small cell lung carcinoma (SCLC) is a rare malignancy of the lung that is usually peripheral and diagnosed after resection. We report an unusual case of centrally located combined SCLC with squamous cell component that was diagnosed on endobronchial lung biopsy.

Small cell lung cancer with endobronchial growth: A case report

“…In this cell type, polypoid lesions with a rough surface covered with necrotic material are the most predominant lesions (16,17). Although SCLC with endobronchial growth is extremely rare, specific cases have been reported (18,19). Ramaraju et al reported an unusual case of centrally-located combined SCLC with a squamous cell component, which was diagnosed by an endo-bronchial lung biopsy (18).…”

“…Although SCLC with endobronchial growth is extremely rare, specific cases have been reported (18,19). Ramaraju et al reported an unusual case of centrally-located combined SCLC with a squamous cell component, which was diagnosed by an endo-bronchial lung biopsy (18). In addition, Lee et al presented the case of a 51-year-old male with SCLC and an endobronchial mass in the left main bronchus (19).…”

“…In addition, Lee et al presented the case of a 51-year-old male with SCLC and an endobronchial mass in the left main bronchus (19). In these cases, the tumors contained elements of SCLC mixed with a component of squamous cell carcinoma (18,19). Patients with combined SCLC have a higher incidence of peripheral lesions, and as a consequence, the central location of the tumor in the present case was unusual.…”