Unusual presentation of chronic eosinophilic pneumonia with mild peripheral eosinophilia

Meena, Rishikesh; Goyal, Abhishek; Keshri, Shashwat Kirti; Khurana, Alkesh Kumar

doi:10.1136/bcr-2020-234914

Cited by 1 publication

(1 citation statement)

References 11 publications

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“…Lab test shows peripheral blood eosinophilia in 90% of cases and elevated immunoglobulin E levels in 50% of cases 5 , 8 . There can be only mild elevation of peripheral blood eosinophils in CEP, so if radiological features are consistent, diagnosis of CEP should be considered 9 . In our case, the eosinophil differential count was elevated and was 30%.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic journey of chronic eosinophilic pneumonia masked as lung cancer: a rare case report

Katwal,

Lamsal,

Bhandari

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Chronic eosinophilic pneumonia (CEP) is an idiopathic condition characterized by unusually high eosinophil infiltration in the lungs’ interstitium and alveolar spaces. It is extremely rare, accounting for fewer than 3% of all Interstitial Lung Diseases. CEP is frequently misdiagnosed as lung cancer, which can have catastrophic consequences for sufferers. When assessing patients with lung disease, doctors should be aware of CEP’s symptoms and take its prognosis into account because it is a curable disorder. Case presentation: A 40-year-old female presented in the outpatient department of Gynecology with a history of abnormal vaginal bleeding for 3 months, and mild shortness of breath without any other significant medical history or under any medications. Physical examination findings were not significant. Clinical Discussion: Ultrasound revealed adenomyosis and a hysterectomy was planned. Chest X-ray revealed lung mass and CT scan showed a well-defined mass with a pleural-based nodule. Histopathology revealed interstitial fibrosis and eosinophilic microabscesses. Chronic eosinophilic pneumonia (CEP) was diagnosed and oral prednisolone was started with a 0.5 mg/kg/day dose. Chest radiographic abnormalities resolved after one month of treatment. Currently, she is asymptomatic. Conclusion: Early recognition and diagnosis of lung masses are essential for prompt treatment with corticosteroids. CEP can mimic lung malignancy and should be considered in patients with related symptoms.

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Section: Discussionmentioning

confidence: 99%