Unusual Presentation of Embryonal Carcinoma of the Testis: A Case Report

Tahri, Youness; Moueqqit, Othman; Mahtar, Mohamed; Ramdani, Mohammed; Nadir, Miry; Bennani, Amal; Barki, Ali

doi:10.7759/cureus.35175

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…Approximately two-thirds of these patients have metastases at the time of diagnosis. 11 Determining the treatment method for metastatic GCT requires multidisciplinary decision making. In uncomplicated cases, starting chemotherapy and, if necessary, performing surgery as an adjuvant is an approved method.…”

Section: Discussionmentioning

confidence: 99%

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Simultaneous bilateral pulmonary and cardiac invasion of metastatic testicular germ cell tumor: A rare case report

Riahi,

Pazoki,

Davani

et al. 2023

Sonography

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A 23‐year‐old man with a history of a testicular germ cell tumor (GCT) that was incompletely treated, is presented with dyspnea. Significant bilateral pulmonary masses were seen on computed tomography (CT). A large, hypermobile mass in the left atrium (LA) as well as mitral valve dysfunction and moderate pulmonary hypertension was detected by transthoracic echocardiography (TTE). Urgent cardiac surgery was performed to prevent the tumor embolism in addition to restore mitral valve function and reduce pulmonary hypertension. Pathologic reports confirmed testicular GCT. GCT metastasis to the heart and lungs is an incredibly rare phenomenon. To our knowledge, this is the first case of simultaneous GCT metastasis to both lungs and LA. This article highlights the importance of cardiac examinations and imaging in germ cell tumor patients. If there is a functional complication for vital organs such as the heart or lungs, surgical interventions are given priority before starting chemotherapy.

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Section: Discussionmentioning

confidence: 99%

“…This type of tumor is seen among young people with an average age of 30 years. Approximately two‐thirds of these patients have metastases at the time of diagnosis 11 …”

Section: Discussionmentioning

confidence: 99%

Simultaneous bilateral pulmonary and cardiac invasion of metastatic testicular germ cell tumor: A rare case report

Riahi,

Pazoki,

Davani

et al. 2023

Sonography

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A case report of recurrent testicular germ cell tumor in a patient with a history of primary pulmonary germ cell tumor and a review of the literature

Tan,

Wu,

Yuan

et al. 2024

Front. Oncol.

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BackgroundCompared to testicular germ cell tumors, the incidence of extragonadal germ cell tumors (EGCTs) is relatively low. While the lungs are a common site for metastasis of malignant germ cell tumors, primary pulmonary germ cell tumors are extremely rare.ObjectiveTo enhance the understanding of the diagnosis and treatment of germ cell tumors, particularly extragonadal germ cell tumors (EGCTs).MethodsA Case Report of Recurrent Testicular Germ Cell Tumor in a Patient with Primary Pulmonary Germ Cell Tumor and a Review of the Literature.Clinical dataThe patient was initially diagnosed with primary pulmonary germ cell tumor and received standard treatment. Five years later, the patient developed a recurrent testicular germ cell tumor. The pathological results from the two surgeries were different, indicating embryonal carcinoma in the first instance and seminoma in the second.ConclusionFor cases with a high suspicion of extragonadal germ cell tumors (EGCTs), early pathological biopsy is essential to confirm the histological subtype and to guide the selection of the most appropriate and sensitive treatment regimen.

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Unusual Presentation of Embryonal Carcinoma of the Testis: A Case Report

Cited by 2 publications

References 15 publications

Simultaneous bilateral pulmonary and cardiac invasion of metastatic testicular germ cell tumor: A rare case report

Simultaneous bilateral pulmonary and cardiac invasion of metastatic testicular germ cell tumor: A rare case report

A case report of recurrent testicular germ cell tumor in a patient with a history of primary pulmonary germ cell tumor and a review of the literature

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