Unusual Presentation of Molar Pregnancy - A Case Report

Iffath, Syeda Mohsina

doi:10.14260/jemds/2014/2105

Cited by 4 publications

(5 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the development of effective chemotherapy has resulted in improved survival of the patients with GTD, hysterectomy remains an important adjunct in the treatment of the selected subset of patients (6). Surgical therapy (hysterectomy) performed with chemotherapy has shown to achieve remission.…”

Section: Resultsmentioning

confidence: 99%

“…They are characterized by a distinct tumor marker b-hCG and have varying tendencies toward local invasion and distant metastasis (5). Vascular invasion and metastasis rarely occur in Invasive mole (6). Demonstration of myometrial vascular mass without the evidence of fetal material on USG in the context of an elevated b-hCG is highly suggestive of GTN (IM) (7,8).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Invasive mole of the uterus: A description of two cases managed by hysterectomy

El-Agwany

Abdeldayem

2015

The Egyptian Journal of Radiology and Nuclear Medicine

View full text Add to dashboard Cite

Gestational trophoblastic disease (GTD) is a term used for a group of pregnancy-related tumors. Gestational trophoblastic neoplasia (GTN), is recognized as the most curable gynecologic malignancy. However, many cases are resistant to first line chemotherapy. We present cases of invasive mole. They were diagnosed as a vesicular mole on ultrasonography and underwent suction and evacuation but vaginal bleeding recurred with plateau and rising B-hcg with intramyometrial vascular lesion. Hysterectomy was done that indicated invasive mole. Patients were cured of their symptoms. Surgical therapy (hysterectomy) with chemotherapy has shown to achieve remission in these cases especially with resistance to chemotherapy and in perimenopause.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Invasive mole of the uterus: A description of two cases managed by hysterectomy

El-Agwany

Abdeldayem

2015

The Egyptian Journal of Radiology and Nuclear Medicine

View full text Add to dashboard Cite

show abstract

“…7 Vascular invasion and metastasis rarely occur in Invasive moles. 8 Demonstration of myometrial vascular mass without the evidence of fetal material on USG in the context of an elevated β-hCG is highly suggestive of GTN (Invasive Mole). 9,10 The incidence of gestational trophoblastic disease varies greatly in different parts of the world, with 0.4 per 1000 births in United States of America to 12.5 per 1000 births in Taiwan.…”

Section: Discussionmentioning

confidence: 99%

Persistent Invasive Mole: A Case Report

Kusuma¹,

Neela²,

Ramavath³

2021

IJOPP

View full text Add to dashboard Cite

Gestational trophoblastic disease is a group of interrelated lesions arising from the trophoblastic epithelium of placenta after abnormal fertilization. It is a disease of women with pregnancy related tumors. Invasive mole, a common manifestation of gestational trophoblastic disease is characterized by villi accompanying trophoblastic overgrowths and invasion which penetrate deep into the myometrium sometimes involving peritoneum or vaginal vault. Here we present a case of persistent invasive mole in a patient who underwent dilation and curettage twice with persistent vaginal bleeding and elevated serum β-human Chorionic Gonadotropin levels. Investigations revealed enlarged uterus with adnexal pathology, Histopathological examination of Dilation and Curettage showed presence of villi and trophoblastic tissue, increased serum β-hCG levels. The patient is successfully treated and managed with methotrexate chemotherapy. This study is focused on the significance of follow-up of the patient as there are more chances of recurrence associated with gestational trophoblastic disease.

show abstract

“…Hysterectomy, unfortunately, remains an important adjunct in the treatment of the selected subset of patients 8,9 , even as these patients have an imperative in preserving fertility.…”

Section: Discussionmentioning

confidence: 99%

Malignant postpartal gestational trophoblastic neoplasm: A rare appearance of equal ultrasonography and operative finding in uterine placental site trophoblastic tumor and choriocarcinoma

Kosta

Mihajlovic

Ivic³

et al. 2020

VOJNOSANIT PREGL

View full text Add to dashboard Cite

Introducton. Frequency of malignant gestational trophoblastic neoplasms (GTN) is estimated at 1.03 cases in 1,000 deliveries with 5 fold greater risk in patients younger than 20 and older than 40 years. Serum value of human chorionic gonadotropin is the most relevant parameter in diagnosis of GTN. In placental site trophoblastic tumor (PSTT), serum levels of chorionic gonadotropin do not have the same significance as they do in other malignant GTN. Definite diagnosis of PSTT is almost always confirmed by immunohistochemistry. Case report. In the course of just a few months (August 2016 to January 2017) in the Clinic for Obstetrics and Gynecology ?Narodni front? in Belgrade, two GTN patients were admitted and treated, with almost equal ultrasonography (pictures), operative findings and postoperative outcome. Due to histopathological and immunohistochemical examinations two different types of malignant GTN were confirmed. The first patient (admitted in August 2016), 26 years old, was admitted for uterine bleeding 11 months after vaginal delivery and histopathological examination confirmed PSTT. The second patient (admitted in January 2017), 27 years old, was admitted 4 months after vaginal delivery because of uterine bleeding. Histopathological examination confirmed choriocarcinoma. Conclusion. Considering the fact that malignant GTN can appear in different types, with different ultrasonography pictures, this report is significant because two distinctly different malignant GTN entities could appear with equal clinical manifestations and equal ultrasound pictures even when they may have very different course of the disease treatment and outcome. Such cases need correct diagnosis which may be reached only after immunohistochemical analysis. The ultrasound patterns, both in gray scale, color flow, and Doppler values, were almost equal in both cases and guided the diagnostic procedures to the final treatment, even regardless of their very different histopathology.

show abstract

Unusual Presentation of Molar Pregnancy - A Case Report

Cited by 4 publications

References 4 publications

Invasive mole of the uterus: A description of two cases managed by hysterectomy

Invasive mole of the uterus: A description of two cases managed by hysterectomy

Persistent Invasive Mole: A Case Report

Malignant postpartal gestational trophoblastic neoplasm: A rare appearance of equal ultrasonography and operative finding in uterine placental site trophoblastic tumor and choriocarcinoma

Contact Info

Product

Resources

About