Unusual presentation of non-Hodgkin′s lymphoma: Case report and review of literature

Abstract

The non-Hodgkin's lymphoma (NHLs) is a diverse group of lymphoid neoplasms, prevalence of which increased since three decades. NHL is diverse in the manner of presentation, response to various treatment and prognosis. NHL usually involves not only lymph nodes but also extranodal sites. Usually, oral manifestation of NHL is secondary to the widespread involvement throughout the body. Oral NHL is relatively rare and difficult to diagnose in clinical setting as it presents as local swelling, pain, discomfort and mimics pyogenic granuloma, periodontal disease, osteomyelitis and other malignancies. Sometimes, oral lesion may present as the early disease (primary site). Careful evaluation of patient and proper investigations is required for correct diagnosis so that patient will receive the treatment in early stage which has a good prognosis. Here, we are presenting the case of low-grade B-cell NHL of palate of a 92-year-old man.

Numb chin as signal for malignancy-primary intraosseous diffuse large B-Cell lymphoma of the mandible

“…[ 11 12 ] Malignant lymphomas are divided into Hodgkin's lymphomas and NHLs and are the most common nonepithelial tumors of the oral cavity. [ 13 14 15 16 ] The disease manifests at a median age of 42 years, with increasing incidence with advancing age. [ 17 ] Within the group of NHLs, 30%–40% are DLBCLs.…”

“…For classification, the Ann Arbor staging system was used. [ 13 ] Nearly, 40% of the patients can be classified as Stage I (single lymph node) or in Stage II (2 lymph nodes on the same side of the diaphragm), and 40% show extranodal manifestation.…”

Incidental case of primary renal lymphoma (PRL) in a patient with chronic hepatitis C infection. Report of a rare case

“…Besides the presence of the renal mass, the following criteria must be met: ( i ) exclusion of concomitant lesions affecting extrarenal visceral organs or lymph nodes at first admission, with the observation that some authors accept the presence of alongside adenopathy [ 24 , 25 ], ( ii ) the absence of leukemic blood picture, and ( iii ) the absence of any sign of myelosuppression [ 4 ].…”

Antioxidant density in plant foods typical in Bulgarian diet and healthy ageing

“…NHL is a heterogeneous group of malignancies characterized by an abnormal clonal proliferation of T-cells, B-cells or both 14 . Most of the adult NHLs are of B-cell origin 15,16 .…”