Unusual Presentation of Rare Case of Papillary Adenofibroma of Cervix in a Young Woman

Abstract

Adenofibroma is an extremely rare benign biphasic neoplasm that is classified into the mixed epithelial and mesenchymal tumor group. These tumors tend to occur in postmenopausal and elderly women. We report the case of a large polypoidal mass per vagina occupying the whole pelvis in a young woman. Preoperative biopsy showed benign epithelial and mullerian mesenchymal components suggestive of mullerian adenofibroma. Total hysterectomy with bilateral salpingectomy was done. The diagnosis of papillary adenofibroma of cervix was made. The total surgery assured complete excision and permitted adequate sampling to exclude malignancy.

Recurrent cervical adenofibroma progressing to adenosarcoma: a rare case report

“…Adenofibroma is a benign lesion, but typically recurs. Recurrent tumors are prone to infiltrate the muscle layer and blood vessels and adequate sampling is needed to exclude adenosarcoma [10,11]. The main reasons for recurrence could be due to incomplete tumor resection or missed diagnosis of borderline tumors with recurrent adenofibroma [10,12].…”

Magnetic Resonance Imaging and Flexible Hysterofiberscopic Findings of a Uterine Adenofibroma: Case Report and Literature Review

“…To date, approximately 30 cases of adenofibroma have been reported in the literature (considering only English publications) ( Table 1 ) [ 1 – 18 ]. Adenofibromas occur primarily in postmenopausal women, of an average age of 57 years, but may also occur in women of reproductive age [ 17 ]. The chief complaints are usually abnormal vaginal bleeding and/or abdominal pain.…”

“…Only approximately 30 cases have been reported to date ( Table 1 ) [ 1 – 18 ]. Attempts have been made to diagnose these tumors using ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), hysteroscopy, and/or biopsy, but these methods were successful in correctly identifying adenofibroma in only three patients [ 3 , 16 , 17 ]. To date, only three patients each were assessed using MRI [ 11 , 12 , 14 ] and hysteroscopy [ 5 , 15 , 16 ].…”