Unusual sites of metastases of carcinoma cervix

Abstract

We present a case of metastatic squamous cell carcinoma cervix with solitary bone metastases to the right tibia and multiple cutaneous metastases. A woman aged 52 years with cancer of the cervix and lung metastases, after 21 months of initial diagnosis and palliative chemotherapy presented with pain in the right knee and multiple nodular skin lesions. Bone scintigraphy revealed intense increased tracer activity in the proximal and mid shaft of the right tibia. Biopsy from the tibial lesion confirmed metastatic squamous cell carcinoma. The presentation, diagnosis and management of this rare case are discussed.

Cancer Cervix With Skin Metastasis - A Case Report With Review of Literature

“…The manifestation in the upper extremities is still rarer. Only six cases have been reported in the upper extremity and after best literature search, our case is first to report in [5][6][7] the forearm region.…”

“…Out of the 329 patients of cancer cervix treated at our centre in last 9 years, this is the first case of skin relapse 10 months after radiotherapy with no evidence of associated locoregional failure, the reported incidence is 0.3%.To the best of our knowledge, only six cases of carcinoma cervix metastasizing to upper extremity have been reported all over the world and this is the first case reported to have [5][6][7] cutaneous manifestation in the forearm region.…”

Apendicitis aguda como manifestación clínica secundaria a metástasis de un carcinoma de células escamosas del cérvix. Reporte de caso

“…Hematogenous spread is rare. Rare cases of this blood-borne metastasis, including bone, skin, fallopian tube, muscle, kidney, and gastrointestinal tract, have been described (10)(11)(12)(13)(14)(15). The differential diagnosis of metastatic appendix tumors includes neuroendocrine tumors, low and high-grade appendiceal mucinous neoplasms, mucinous adenocarcinoma, colonic-type adenocarcinoma, goblet cell carcinoma, mesenchymal tumors (GIST, desmoid, leiomyoma, leiomyosarcoma), non-carcinoid tumors (ganglioneuroma, pheochromocytoma, paraganglioma), sarcomas (HIV-associated Kaposi sarcoma, desmoplastic small round cell tumors), neuroectodermal and nerve sheath tumors (schwannoma, neurofibroma), lymphomas, and metastasis (2).…”

Metástasis pulmonares de carcinoma de cérvix de células escamosas en asociación con tuberculosis. Reporte de un caso

“…Los sitios habituales de metástasis del carcinoma de cérvix son de manera linfática, la forma hematógena es sumamente rara y, si se presenta, los sitios habituales son el hueso y el pulmón, como es el caso de nuestra paciente 11 .…”