Unusual transformations of aliphatic nitro compounds in a flow reactor in high-pressure isopropanol on alumina. Part 2. Formation of esters

Synthesis of Spiro[indole-3,5′-isoxazoles] with Anticancer Activity via a Formal [4 + 1]-Spirocyclization of Nitroalkenes to Indoles

“…Reaction progress and purity of isolated compounds were controlled by thin-layer chromatography (TLC) on Silufol UV-254 plates, eluting with hexanes/EtOAc mixture (4:1). Indoles 4d , 4h , and 4j , as well as nitroalkene 3e were synthesized according to known procedures. All other reagents and solvents were purchased from commercial vendors and used as received.…”