Unusual Tumors Involving the Head and Neck Region

Vilenski, Leonid; Potti, Anil; Mehdi, Syed

doi:10.1200/jco.2001.19.21.4177

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…In the literature review of the atypical clinical features of metastatic prostate cancers, the involvement of CNs 2,3,5,6,7,8 and 12 was encountered even though it is rare. [ 2 3 5 8 9 10 ] While most of these involvements consist of known prostate cancer patients, the number of cases who are diagnosed with CN palsy is very small as in our case. Clinicians should remain vigilant in terms of prostate carcinoma metastasis in male patients with CN palsy.…”

Section: Discussionmentioning

confidence: 70%

“…It has been suggested that the radiotherapy may lead to partial neurological improvement and it should be immediately started when the CN involvement. [ 9 10 ] Based on the rapid neurological improvement in our case, we consider that if the neural structure is in a surgically decompressed localization, surgical excision may be an alternative treatment. Therefore, we preferred orbitozygomatic craniotomy to orbitotomy for wide sixth nerve decompression.…”

Section: Discussionmentioning

confidence: 96%

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Calvarial-orbital metastasis of prostate carcinoma which was diagnosed with sixth cranial nerve palsy

et al. 2017

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Sixth nerve palsy is frequently due to infectious orbital lesions, trauma, elevated intracranial pressure, brainstem lesions, and vasculopathies. Here, we describe a rare cause of sixth cranial nerve (CN) palsy secondary to calvarial and orbital metastasis of prostate carcinoma. The diagnosis of the prostate carcinoma with sixth CN palsy is a very rare condition. A 66-year-old male patient presented with complaints of blurred vision, double vision, and inability to move outward in the right eye for 3 weeks. Magnetic resonance imaging revealed a right orbitocalvarial mass and the mass surgically removed completely. Pathologic findings were compatible with prostate adenocarcinoma metastasis. After surgical removal, significant improvement in sixth CN palsy was observed.

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 96%

Calvarial-orbital metastasis of prostate carcinoma which was diagnosed with sixth cranial nerve palsy

et al. 2017

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Unilateral Exophthalmos Revealing Metastatic Prostate Cancer

Adli

Elammari

Elfassi

et al. 2012

Urology

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A 73-year-old man with congestion and mild proptosis of the left eye

2016

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HistoryA 73-year-old man presented to the Department of Ophthalmology, Amala Institute of Medical Sciences, Kerala, with mild congestion of left eye. He believed that his symptoms began after accidental exposure of his eyes to medicated oil used during a massage session, as part of traditional medical treatment he was taking. He was diagnosed with toxic conjunctivitis and treated with loteprednol eyedrops. At his follow-up visit on the third day, he complained that his left eye had not improved and that it was starting to "bulge out."The patient denied vision loss, double vision, headache, or other systemic symptoms. He had undergone bilateral orchidectomy and radiotherapy for prostate carcinoma 3 years earlier and was now on hormone therapy with bicalutamide. He had undergone thyroidectomy for hyperthyroidism 15 years previously and was now onlevothyroxine. Ocular history was remarkable for uneventful cataract extraction in both eyes with IOL placement 20 years previously. ExaminationOn initial examination, best-corrected visual acuity was 20/20 in each eye. Color vision was normal in both eyes. There was periorbital fullness and partial ptosis of the left eye. Palpation revealed apainless, firm swelling along the lateral one-third of superior orbital margin. It was found to displace the globe inferiorly ( Figure 1A). Hertel exophthalmometry measured 16 mm in the right eye and 22 mm in the left eye ( Figure 1B). Ocular motility was full on the right side; the left eye showed generalized restriction and complete loss of elevation ( Figure 1C).Slit-lamp examination of the anterior and posterior segments was entirely normal except for temporal bulbar conjunctival congestion with chemosis in left eye. Pupils were reactive, with no afferent pupillary defect.General examination did not reveal any abnormal cervical lymph nodes. Cranial nerve evaluation was within normal limits. Ancillary TestingRoutine blood testing, thyroid function tests, and prostate specific antigen (PSA; 0.1 ng/ml) were within normal limits. Computed tomography (CT) of brain and orbit demonstrated an enhancing lytic lesion, with a significant soft tissue component and calcification. It measured 22 × 35 × 34 mm and involved the left frontal bone encroaching on the lateral wall of orbit. The lesion was found to indent the globe on its superior aspect. Both the superior rectus and superior oblique muscles appeared to be involved. The left optic nerve was free. These findings were suggestive of left orbital metastasis with intracranial extension (Figure 2).

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Unusual Tumors Involving the Head and Neck Region

Cited by 3 publications

References 6 publications

Calvarial-orbital metastasis of prostate carcinoma which was diagnosed with sixth cranial nerve palsy

Calvarial-orbital metastasis of prostate carcinoma which was diagnosed with sixth cranial nerve palsy

Unilateral Exophthalmos Revealing Metastatic Prostate Cancer

A 73-year-old man with congestion and mild proptosis of the left eye

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