Unveiling the bioactivity of Allium triquetrum L. lipophilic fractions: chemical characterization and in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus

Rabah, Samia; Kouachi, K.; Ramos, Patrícia A. B.; Gomes, Ana T. P. C.; Almeida, Adelaide; Haddadi‐Guemghar, Hayate; Madani, Khodir; Silvestre, Armando J. D.; Santos, Sónia A.O.

doi:10.1039/d0fo00769b

Cited by 12 publications

(7 citation statements)

References 31 publications

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“…Innovation in BioPolymer-based Functional Materials and Bioactive Compounds, from the Portuguese associate laboratory CICECO–Aveiro Institute of Materials [ 41 ] at the University of Aveiro in Portugal. Among other research topics [ 42 , 43 , 44 , 45 ], this interdisciplinary group exercises research activities devoted to the use of renewable feedstocks for the extraction of high-value compounds from agroforest and industrial by-products [ 39 , 40 , 46 ], the valorisation of vegetable oils for the production of monomers and polymers [ 47 , 48 , 49 , 50 , 51 ], the design of biobased polyesters [ 52 , 53 , 54 , 55 ], and, in particular, the development of a panoply of natural polysaccharide- and protein-based materials [ 6 , 56 , 57 , 58 , 59 , 60 , 61 , 62 ].…”

Section: Introductionmentioning

confidence: 99%

Natural Polymers-Based Materials: A Contribution to a Greener Future

et al. 2021

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Natural polymers have emerged as promising candidates for the sustainable development of materials in areas ranging from food packaging and biomedicine to energy storage and electronics. In tandem, there is a growing interest in the design of advanced materials devised from naturally abundant and renewable feedstocks, in alignment with the principles of Green Chemistry and the 2030 Agenda for Sustainable Development. This review aims to highlight some examples of the research efforts conducted at the Research Team BioPol4fun, Innovation in BioPolymer-based Functional Materials and Bioactive Compounds, from the Portuguese Associate Laboratory CICECO–Aveiro Institute of Materials at the University of Aveiro, regarding the exploitation of natural polymers (and derivatives thereof) for the development of distinct sustainable biobased materials. In particular, focus will be given to the use of polysaccharides (cellulose, chitosan, pullulan, hyaluronic acid, fucoidan, alginate, and agar) and proteins (lysozyme and gelatin) for the assembly of composites, coatings, films, membranes, patches, nanosystems, and microneedles using environmentally friendly strategies, and to address their main domains of application.

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Section: Introductionmentioning

confidence: 99%

Natural Polymers-Based Materials: A Contribution to a Greener Future

et al. 2021

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“…This last author reported the antibacterial effect of octacosanoic acid evenly, a saturated fatty acid which is identified in this study. The synergic effect of different compounds contained in these extracts is eventually evoked by analysing the MICs obtained in this study mainly against B. cereus and E. coli , a hypothesis that is always put forward in such studies [ 69 , 79 ].…”

Section: Resultsmentioning

confidence: 99%

Lipophilic Compounds and Antibacterial Activity of Opuntia ficus-indica Root Extracts from Algeria

Benramdane

Chougui

Ramos

et al. 2022

IJMS

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The chemical composition, investigated by gas chromatography-mass spectrometry, and antibacterial activity of lipophilic extractives of three varieties of Opuntia ficus-indica roots from Algeria are reported in this paper for the first time. The results obtained revealed a total of 55 compounds, including fatty acids, sterols, monoglycerides and long chain aliphatic alcohols that were identified and quantified. β-Sitosterol was found as the major compound of the roots of the three varieties. Furthermore, considerable amounts of essential fatty acids (ω3, ω6, and ω9) such as oleic, linoleic, and linolenic acids were also identified. The green variety was the richest among the three studied varieties. The antibacterial activity, evaluated with disc diffusion method, revealed that lipophilic extracts were effective mainly against Gram-positive Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) (19~23 mm). Gram-negative strains mainly Pseudomonas aeruginosa gave an inhibition zone of 18 mm, which is considered high antibacterial activity. The minimal inhibitory concentrations of the tested bacteria revealed interesting values against the majority of bacteria tested: 75–100 µg mL−1 for Bacillus sp., 250–350 µg/mL for the two Staphylococcus strains, 550–600 µg mL−1 for E. coli, and 750–950 µg mL−1 obtained with Pseudomonas sp. This study allows us to conclude that the lipophilic fractions of cactus roots possess interesting phytochemicals such as steroids, some fatty acids and long chain alcohols that acted as antibiotic-like compounds countering pathogenic strains.

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“…Based on the GC-MS analysis and our previous work, a total intensity chromatogram image of SAVEP is shown in Figure 1 . Referring to the quantitative method of GC-MS experiment conducted by Rabah [ 23 ], we chose the relative quantitative method to quantify the detected polyphenols. Our study showed a total of 703 peaks in the sample.…”

Section: Resultsmentioning

confidence: 99%

Polyphenols Extracted from Shanxi-Aged Vinegar Inhibit Inflammation in LPS-Induced RAW264.7 Macrophages and ICR Mice via the Suppression of MAPK/NF-κB Pathway Activation

et al. 2021

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Shanxi-aged vinegar, a traditional Chinese grain-fermented food that is rich in polyphenols, has been shown to have therapeutic effects on a variety of diseases. However, there has been no comprehensive evaluation of the anti-inflammatory activity of polyphenols extracted from Shanxi-aged vinegar (SAVEP) to date. The anti-inflammatory activities of SAVEP, both in RAW 264.7 macrophages and mice, were extensively investigated for the potential application of SAVEP as a novel anti-inflammatory agent. In order to confirm the notion that polyphenols could improve inflammatory symptoms, SAVEP was firstly detected by gas chromatography mass spectrometry (GC-MS). In total, 19 polyphenols were detected, including 12 phenolic acids. The study further investigated the protective effect of SAVEP on lipopolysaccharide-induced inflammation in RAW264.7 macrophages and ICR mice. The results showed that compared with those of the model group, SAVEP could remarkably recover the inflammation of macrophage RAW264.7 and ICR mice. SAVEP can normalise the expression of related proteins via the suppression of MAPK/NF-κB pathway activation, inhibiting the expression of iNOS and COX-2 proteins, and consequently the production of inflammatory factors, thus alleviating inflammatory stress. These results suggest that SAVEP may have a potential function against inflammation.

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Unveiling the bioactivity of Allium triquetrum L. lipophilic fractions: chemical characterization and in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus

Abstract: Allium triquetrum L. bulbs, flowers and leaves are proved to be valuable sources of value-added lipophilic compounds, specifically as antibacterial agents against methicillin-resistant Staphylococcus aureus.

Cited by 12 publications

References 31 publications

Natural Polymers-Based Materials: A Contribution to a Greener Future

Natural Polymers-Based Materials: A Contribution to a Greener Future

Lipophilic Compounds and Antibacterial Activity of Opuntia ficus-indica Root Extracts from Algeria

Polyphenols Extracted from Shanxi-Aged Vinegar Inhibit Inflammation in LPS-Induced RAW264.7 Macrophages and ICR Mice via the Suppression of MAPK/NF-κB Pathway Activation

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