Groundwater is a vital drinking water source, especially in arid regions, sustaining both urban and rural populations. Its quality is influenced by natural (hydrogeological) and human-driven (demographic, policy) factors, which may pose significant public health risks, especially for communities relying on unregulated water supplies. This study addresses critical gaps by examining groundwater vulnerability and contamination disparities, emphasizing their implications for public health and equitable resource management. It analyzes the impact of socio-hydrogeological factors on arsenic and nitrate levels in groundwater-supplied systems in Arizona, U.S. Methods include spatial analysis, ANOVA, multivariate regression, and cluster analysis. Significant disparities in arsenic and nitrate contamination, including exceedances of regulatory limits, were observed across supply types, aquifer characteristics, jurisdictional oversights, and groundwater management areas. Domestic wells and community water systems showed distinct contamination risks. Groundwater vulnerability was influenced by geological differences (karst vs. alluvial aquifers) and regulatory oversight, with Tribal and State systems facing unique challenges and resource needs. Socioeconomic disparities were evident, with minority communities, institutional facilities, rural areas, and specific housing types disproportionately exposed to higher contaminant levels. These findings unveil the intersection of race, socioeconomic status, and public health risks, offering an adaptable framework for addressing similar groundwater challenges in arid and semi-arid regions globally. This study is innovative in its focus on policy distinctions between private and regulated wells, karst and alluvial aquifers, and State and Tribal jurisdictions. It emphasizes the need for targeted vulnerability assessments and remediation strategies that integrate geological, hydrological, and regulatory factors to address risk disparities in vulnerable communities. These environmental inequities underscore the urgent need for stronger regulations and strategic resource allocation to support marginalized communities. The study recommends enhancing monitoring protocols, prioritizing resource distribution, and implementing targeted policy interventions to ensure equitable and sustainable access to safe drinking water in arid regions.
