2024
DOI: 10.3844/ojbsci.2024.302.312
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Unveiling the Impact of Endogenous Sialidases on Human Non-Infectious Disease Pathogenesis

Raisa Sergeevna Surkova,
Anastasia Vladimirovna Poznyak,
Dmitry Alexandrovich Kashirskikh
et al.

Abstract: In our review, we have compiled existing information regarding the role of endogenous sialidases (neuraminidases) in the initiation and development of various non-infectious processes in humans. Precisely, pathologies of the cardiovascular system, tumor formations, neurological and metabolic disorders, and hereditary diseases. Sialidases appeared to be widely involved in a variety of human pathologies. An increase or decrease in the enzymatic activity of sialidase can be a triggering factor in the pathogenesis… Show more

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