Unveiling the Mpox menace: exploring the intricacies of a zoonotic virus and clinical implications

Sharma, Eshita; Malhotra, Sakshi; Kaul, Shreya; Jain, Nidhi; Nagaich, Upendra

doi:10.1016/j.diagmicrobio.2023.116024

Diagnostic Microbiology and Infectious Disease

2023

DOI: 10.1016/j.diagmicrobio.2023.116024

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Unveiling the Mpox menace: exploring the intricacies of a zoonotic virus and clinical implications

Eshita Sharma

Sakshi Malhotra

Shreya Kaul

et al.

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Cited by 2 publications

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“…12 The potential correlation between these neurological manifestations and the invasive nature of mpox in brain tissue, as elucidated in certain infected animals, necessitates a comprehensive mechanistic understanding. 13 Mpox may enter the brain parenchyma and show neuroinvasive propensity. 14 This potential can be mediated via two suggested routes, such as olfactory epithelium and haematogenous penetration through infected monocytes/macrophages.…”

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confidence: 99%

Overview of reemerging mpox infection with a focus on neurological manifestations

Alissa,

Alghamdi,

Alghamdi

2024

Reviews in Medical Virology

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Mpox, a reemerging zoonotic disease caused by the mpox virus, has garnered increasing attention due to its potential for severe clinical manifestations. While the cutaneous and systemic presentations of mpox have been well‐documented, its neurological complications have recently emerged as an area of concern. This review provides a brief overview of the neurological aspects of mpox infection, highlighting the key findings and challenges in understanding and managing these complications. Neurological manifestations in mpox patients range from mild symptoms such as headaches and dizziness to more severe conditions, including encephalitis and seizures. The pathogenesis of neurological involvement is not yet fully elucidated but is thought to involve viral dissemination to the central nervous system. This dissemination may occur through haematogenous or neuronal routes, contributing to the diverse clinical spectrum observed. Early recognition and diagnosis of neurological complications in mpox are crucial for implementing appropriate therapeutic interventions and improving patient outcomes.

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mentioning

confidence: 99%

Overview of reemerging mpox infection with a focus on neurological manifestations

Alissa,

Alghamdi,

Alghamdi

2024

Reviews in Medical Virology

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Entropy-Driven, Integrative Bioinformatics Approaches Reveal the Recent Transmission of the Monkeypox Virus from Nigeria to Multiple Non-African Countries

Sarkar,

Bhattacharya,

Agoramoorthy

et al. 2023

Mol Biotechnol

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Unveiling the Mpox menace: exploring the intricacies of a zoonotic virus and clinical implications

Cited by 2 publications

References 64 publications

Overview of reemerging mpox infection with a focus on neurological manifestations

Overview of reemerging mpox infection with a focus on neurological manifestations

Entropy-Driven, Integrative Bioinformatics Approaches Reveal the Recent Transmission of the Monkeypox Virus from Nigeria to Multiple Non-African Countries

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