Unveiling the Relevance of the Oral Cavity as a Staphylococcus aureus Colonization Site and Potential Source of Antimicrobial Resistance

Campos, Joana; Pires, Marinês Ferreira; Sousa, Marta; Campos, Carla; Costa, Carolina F. F. A.

doi:10.3390/pathogens12060765

Cited by 5 publications

(2 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…16 In another study, Campos et al reported the prevalence of S. aureus in the oral and nasal cavities, showing 13.9% from the nasal cavity, 12.0% from the oral cavity, and 9.9% from both sites in healthy volunteers (average age: 21.83 ± 3.53 years). 17 Vanzato Palazzo et al reported that the prevalence of S. aureus and MRSA was 47.6% and 4.1%, respectively, in the saliva of 340 healthcare workers. 35 Petti et al also reported that the prevalence of S. aureus and MRSA was 8.9% and 1.9%, respectively, in oral swabs of 157 dental students.…”

Section: Discussionmentioning

confidence: 99%

“…[11][12][13] In addition, the emergence of methicillin-resistant S. aureus (MRSA) has become more serious for chemotherapeutic treatment. 14,15 S. aureus, including MRSA, is also isolated from the oral cavity 16,17 and is a causative pathogen for aspiration pneumonia. [18][19][20] Aspiration pneumonia is caused by aspiration of food or saliva, which allows bacteria to enter the respiratory system and cause infection.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Oral and rectal colonization of methicillin‐resistant Staphylococcus aureus in long‐term care facility residents and their association with clinical status

Kusaka,

Haruta,

Kawada‐Matsuo

et al. 2024

Microbiology and Immunology

View full text Add to dashboard Cite

Staphylococcus aureus is a commensal bacterium in humans, but it sometimes causes opportunistic infectious diseases such as suppurative skin disease, pneumonia, and enteritis. Therefore, it is important to determine the prevalence of S. aureus and methicillin‐resistant S. aureus (MRSA) in individuals, especially older adults. In this study, we investigated the prevalence of S. aureus and MRSA in the oral cavity and feces of residents in long‐term care facilities (LTCFs). S. aureus was isolated from the oral cavity of 61/178 (34.3%) participants, including 28 MRSA‐positive participants (15.7%), and from the feces of 35/127 (27.6%) participants, including 16 MRSA‐positive participants (12.6%). S. aureus and MRSA were isolated from both sites in 19/127 individuals (15.0%) and 10/127 individuals (7.9%), respectively. Among 19 participants with S. aureus isolation from both sites, 17 participants showed the same sequence type (ST) type. Then, we analyzed the correlation of S. aureus and MRSA in the oral cavity and rectum with the participant's condition. S. aureus and MRSA positivity in the oral cavity was significantly related to tube feeding, while there was no correlation of rectal S. aureus/MRSA with any factors. Our findings regarding the oral inhabitation of MRSA and its risk factors indicate the importance of considering countermeasures against MRSA infection in LTCFs.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Oral and rectal colonization of methicillin‐resistant Staphylococcus aureus in long‐term care facility residents and their association with clinical status

Kusaka,

Haruta,

Kawada‐Matsuo

et al. 2024

Microbiology and Immunology

View full text Add to dashboard Cite

show abstract

Determining the Relationship of Bacteria Associated With Dental Disease and Infective Endocarditis

Indermun,

Baswaraj,

Regunath

et al. 2024

Infect Dis Clin Pract

View full text Add to dashboard Cite

Objectives Poor oral hygiene is a risk factor for bacteremia and infective endocarditis (IE). The purpose of this study was to determine the relationship of bacteria commonly associated with dental disease in native valve and prosthetic valve endocarditis patients at a tertiary center in Missouri. Methods This retrospective cross-sectional analysis reviewed the electronic medical records of patients diagnosed with definite IE, per the modified Duke criteria, at the University of Missouri Hospital between September 2015 and April 2019. Medical records were screened using International Classification of Diseases, Tenth Edition, code for IE (I 33) and further validated by screening echocardiography for intracardiac vegetations. Demographics, type of IE, echocardiographic findings, blood culture results, and relevant medical and dental data were recorded, and a descriptive analysis performed. Results One hundred twenty-seven patients with 134 episodes (mean = 51.1 years, SD ± 17.7 yrs; M: F = 1:1) satisfied the criteria. Of these, 19 (14.2%) episodes were identified to have blood culture results positive for bacteria associated with the oral cavity. Seventy-seven (57.5%) episodes were related to Staphylococcus aureus. Staphylococcus aureus is a constituent of normal oral flora and can contribute to oral disease and IE, but the connection between the 2 remains contentious in both medical and dental practice. Remarkably, 72 (53.8%) medical records lacked documentation of dental history and oral examination. Conclusions A significant proportion of IE cases are from bacteria associated with the oral cavity, advocating for routine dental evaluation and treatment as an essential component of care of patients with IE.

show abstract

The effect of soaking heat-polymerized acrylic resin denture base in avocado seed extract (Persea americana Mill.) on the inhibition of denture-plaque microorganisms biofilm growth

Angela,

Wahyuni,

Halim

2024

F1000Res

View full text Add to dashboard Cite

Background Heat polymerized acrylic (HPA) resins are known to have high porosity that contributes to increased surface roughness and microcrack formation in stress areas. This facilitates the attachment and growth of polymicrobial biofilms contributing to increased antimicrobial resistance. Many research had been carried out on avocado seeds, but no research that studies the effect of avocado seeds on denture-plaque microorganism biofilm on HPA resin has been found. Methods This study used 144 samples (n=144), namely HPA resin discs covered with mono-species and polymicrobial biofilms consisting of Candida albicans, Candida glabrata, Actinomyces odontolyticus, Streptococcus gordonii, and Staphylococcus aureus. The discs were soaked for 8 hours in the 5%, 10%, 15%, 20% avocado seed extract, positive control (alkaline peroxide), and negative control (aquadest). Each disc was shaken with a vortex mixer for 1 minute, and 100 μL was added into 96-well microplates with three times repetition and incubated for 24 hours. The inhibition values were determined from the percentage inhibition value formula which required absorption values from a microplate reader (595 nm). Results In this research, it was found that the MBIC50 of avocado seed extract against the mono-species of C. albicans (5%), C. glabrata (5%), A. odontolyticus (15%), S. gordonii (15%), S. aureus (10%), while against the biofilm was 20%. There was a significant effect of soaking HPA resin in avocado seed extract of 5%, 10%, 15%, 20% on the inhibition of mono-species and polymicrobial biofilms of denture-plaque microorganisms with a value of p<0.001 (p<0.05). Conclusion The MBIC50 of avocado seed extract in polymicrobial biofilm group was higher than that in the mono-species biofilm groups. Although alkaline peroxide showed higher inhibition value than that of the MBIC50 in polymicrobial biofilm group, 20% avocado seed extract was effective in inhibiting polymicrobial biofilm because it was able to inhibit more than 50% polymicrobial biofilm.

show abstract

Unveiling the Relevance of the Oral Cavity as a Staphylococcus aureus Colonization Site and Potential Source of Antimicrobial Resistance

Cited by 5 publications

References 33 publications

Oral and rectal colonization of methicillin‐resistant Staphylococcus aureus in long‐term care facility residents and their association with clinical status

Oral and rectal colonization of methicillin‐resistant Staphylococcus aureus in long‐term care facility residents and their association with clinical status

Determining the Relationship of Bacteria Associated With Dental Disease and Infective Endocarditis

The effect of soaking heat-polymerized acrylic resin denture base in avocado seed extract (Persea americana Mill.) on the inhibition of denture-plaque microorganisms biofilm growth

Contact Info

Product

Resources

About