2013
DOI: 10.1016/j.jnutbio.2013.02.002
|View full text |Cite
|
Sign up to set email alerts
|

Up-regulation of vitamin B1 homeostasis genes in breast cancer

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
17
0

Year Published

2013
2013
2024
2024

Publication Types

Select...
9

Relationship

2
7

Authors

Journals

citations
Cited by 27 publications
(18 citation statements)
references
References 43 publications
1
17
0
Order By: Relevance
“…An elevation of SLC19A3 methylation was detected in the plasma of early- and advanced-stage breast cancer patients as well as gastric cancer [23]. Recently, our group discovered a significant increase in the gene expression of TPK1, SLC19A2 , and SLC25A19 in breast cancer tissue samples compared to normal breast tissue [24]. A slight decrease in SLC19A3 gene expression was also found in concordance with previous findings.…”
Section: Reviewsupporting
confidence: 75%
“…An elevation of SLC19A3 methylation was detected in the plasma of early- and advanced-stage breast cancer patients as well as gastric cancer [23]. Recently, our group discovered a significant increase in the gene expression of TPK1, SLC19A2 , and SLC25A19 in breast cancer tissue samples compared to normal breast tissue [24]. A slight decrease in SLC19A3 gene expression was also found in concordance with previous findings.…”
Section: Reviewsupporting
confidence: 75%
“…TPK1, SLC19A2/THTR1 and SLC25A19/TPC have been shown to be up-regulated in breast cancer in both patients and cell lines [16]. Unlike TPK1 and THTR1 knockdown, TPC knockdown did not cause an increase in radiosensitivity (Fig.…”
Section: Discussionmentioning
confidence: 95%
“…Liu et al showed that the addition of thiaminase into cell culture media containing thiamine had a significant inhibitory effect on growth of breast cancer cells [28]. Also a pegylated version of thiaminase was capable in delaying tumor growth and prolonging survival in an RS4 leukemia xenograft model [29, 30] and it is seen that the increased glycine and thiamine are linked.…”
Section: Discussionmentioning
confidence: 99%