2021
DOI: 10.21203/rs.3.rs-392135/v2
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Up-regulation thioredoxin contributes to inhibite diabetic hearing impairment

Abstract: Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia. An association between DM and hearing impairment has been widely discussed. It’s essential to find effective prevetion or diagnosis of diabetic hearing loss. Thioredoxin (Trx) is a small molecule protein (12kDa) and plays biological functions such as anti-apoptotic, transcriptional regulation. In this study, our aim is to clarify the protective effect of Trx on diabetic hearing loss to find the early potential therapeutic ta… Show more

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