Up-to-Date Management of Carcinoma of the Penis

Lymphadenectomy for squamous cell carcinoma of the penis. Part 2: The role and technique of lymph node dissection

“…In the absence of randomized studies it is unclear whether survival is improved by adding radiation therapy. Combination chemotherapy appears to provide major responses in about two-thirds of the patients; the tumour is made resectable in half and with durable disease-free survival in 15±30% [54]. These values are based on two combination chemotherapy regimens, i.e.…”

“…The major goal of this treatment is increased local control. Another treatment is adjuvant combination chemotherapy; the combination of vincristine, bleomycin and methotrexate was used from 1979 to 1990 in 25 patients after LND [54]. Most showed extranodal spread and seven had pelvic metastases.…”

A Different Application of the Unilobed Flap

“…Recently, Mohs microsurgery, laser ablation, and radiation therapy have all been used in the treatment of low-grade penile cancer. [3][4][5] Penile cancer involving the glans penis and distal shaft is managed using partial penectomy in an attempt to leave sufficient penile length for upright voiding and possibly sexual intercourse. For high-grade locally advanced cancer and for lesions involving the proximal penile shaft, total penectomy is recommended.…”

Iliac nodal metastases from carcinoma of the penis treated surgically

“…From the series shown in Table 2 the survival rate is 15% (10 of 67). Adjuvant therapy is needed to improve survival in these patients and some studies have tried to determine the value of chemotherapy in managing nodal metastases from squamous cell carcinoma of the penis [14–16]. Corral et al.…”