Update in cutaneous manifestations of COVID-19: Special populations

Abstract

Cutaneous abnormalities were among the fi rst clinical fi ndings reported in patients infected with SARS-CoV-2 at the onset of the COVID-19 pandemic, but the signifi cance was initially unclear. Correlations have since been drawn between many of these cutaneous eruptions and their diagnostic or prognostic value. Additionally, COVID-19 vaccines have generated acute and delayed cutaneous reactions with which clinicians should be familiar. In this narrative review, we update the cutaneous abnormalities associated with COVID-19 infection for pediatric and non-White populations, and common cutaneous reactions to COVID-19 vaccines. KEY POINTSThere has been an increase in cutaneous manifestations together with and following COVID-19 infection and messenger RNA vaccination, respectively. Unique manifestations have been described in children, including erythema multiforme, acute hemorrhagic edema of infancy, papular acrodermatitis of childhood, and various skin changes in multisystem infl ammatory syndrome in children.Adenoviral vector vaccine appears to result in vaccineinduced thrombotic thrombocytopenia in some patients.