Update in the management of penile cancer

Caso, Jorge; Rodríguez, Alejandro; Correa, José Jaime; Spiess, Philippe E.

doi:10.1590/s1677-55382009000400003

Cited by 15 publications

(10 citation statements)

References 79 publications

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“…This has prompted newer penispreserving techniques to come into light which provides both physical and psychological solution to these people. These options have brought about a major shift from Bmutilationt o Bconservation.^Many authors in literature have expressed similar views [3][4][5].…”

Section: Introductionmentioning

confidence: 95%

Organ Preservation Surgery for Carcinoma Penis

Yuvaraja

Waigankar

Dharmadhikari

et al. 2016

Indian J Surg Oncol

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Carcinoma of the penis is not uncommon in India. A sizeable number of patients do not report to the doctors in fear of mutilation to the organ and hence subsequently end up with advanced disease. Many patients with T1 or T2 disease when carefully selected are amenable to organ-preserving penile procedures including surgery, topical therapy, laser, and radiation therapy. Identification of appropriate patients and institution of these treatments has been noted to produce oncologically comparable results to extirpative surgeries. In this article, we review the criteria to identify patients qualifying for organ-preserving treatments and also review outcomes with a variety of penile-preserving procedures.

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Section: Introductionmentioning

confidence: 95%

Organ Preservation Surgery for Carcinoma Penis

Yuvaraja

Waigankar

Dharmadhikari

et al. 2016

Indian J Surg Oncol

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“…54–57 When considering one imaging modality to evaluate the stage of the primary lesion and lymph node status, MRI seems to be the best choice to not only enhance but also potentially replace the physical examination in patients in whom the inguinal region is difficult to assess (eg, morbidity, previous chemo/RT). 54,58 …”

Section: Management Of Regional Lymph Nodesmentioning

confidence: 99%

Penile Cancer

Clark¹,

Spiess²,

Agarwal³

et al. 2013

J Natl Compr Canc Netw

159

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Squamous cell carcinoma of the penis represents approximately 0.5% of all cancers among men in the United States and other developed countries. Although rare, it is associated with significant disfigurement, and only half of the patients survive beyond 5 years. Proper evaluation of both the primary lesion and lymph nodes is critical, because nodal involvement is the most important factor of survival. The NCCN Clinical Practice Guidelines in Oncology for Penile Cancer provide recommendations on the diagnosis and management of this devastating disease based on evidence and expert consensus.

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“…The mainstay of surgical treatment relies upon wide excision including partial penectomy and total penectomy. More recently, a variety of operative techniques and therapeutic strategies have been developed to reconcile good functional and psychological outcomes with sufficient oncological control through organ sparing techniques [9, 10]. …”

Section: Introductionmentioning

confidence: 99%

Primary penile cancer organ sparing treatment

Sosnowski

Kuligowski

Kuczkiewicz

et al. 2016

CEJU

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IntroductionSurgical treatment of penile cancer is usually associated with mutilation; alterations in self-esteem and body image; affecting sexual and urinary functions; and declined health-related quality of life. Recently, organ sparing treatment has appeared and led to limiting these complications.Material and methodsAn extensive review of the literature concerning penile-preserving strategies was conducted. The focus was put on indications, general principles of management, surgical options and reconstructive techniques, the most common complications, as well as functional and oncological outcomes.ResultsAnalyzed methods, e.g.: topical chemotherapy, laser ablation therapy, radiotherapy, Moh’s microscopic surgery, circumcision, wide local excision, glans resurfacing and glansectomy are indicated in low-stage tumors (Tis, Ta-T2). After glansectomy, reconstruction is also possible.ConclusionsOrgan sparing techniques may achieve good anatomical, functional, and psychological outcomes without compromising local cancer control, which depends on early diagnosis and treatment. Penile sparing strategies are acceptable treatment approaches in selected patients with low-stage penile cancer after establishing disease-risk and should be considered in this population.

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Update in the management of penile cancer

Cited by 15 publications

References 79 publications

Organ Preservation Surgery for Carcinoma Penis

Organ Preservation Surgery for Carcinoma Penis

Penile Cancer

Primary penile cancer organ sparing treatment

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