Update on Clinical Trials in Dysphagia

Logemann, Jeri A.

doi:10.1007/s00455-006-9017-8

Cited by 28 publications

(16 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Logemann [27] in a consecutive series of 53 VMBS reported that pressure generation during swallowing and airway protection are the most frequent disorders observed (reduced tongue base retraction and reduced tongue strength). A more frequent reduction in tongue base movement was described in patients with oropharynx and larynx cancer.…”

Section: Resultsmentioning

confidence: 99%

Dysphagia in Head and Neck Cancer Patients: Pretreatment Evaluation, Predictive Factors, and Assessment during Radio-Chemotherapy, Recommendations

Denaro

Merlano

Russi

2013

Clin Exp Otorhinolaryngol

125

102

View full text Add to dashboard Cite

Progress in head and neck cancer (HNC) therapies has improved tumor response, loco-regional control, and survival. However, treatment intensification also increases early and late toxicities. Dysphagia is an underestimated symptom in HNC patients. Impairment of swallowing process could cause malnutrition, dehydration, aspiration, and pneumonia. A comprehensive literature review finalized in May 2012 included searches of electronic databases (Medline, Embase, and CAB abstracts) and scientific societies meetings materials (American Society of Clinical Oncology, Associazione Italiana Radioterapia Oncologica, Associazione Italiana di Oncologia Cervico-Cefalica, American Head and Neck Society, and European Society for Medical Oncology). Hand-searches of HNC journals and reference lists were carried out. Approximately one-third of dysphagia patients developed pneumonia requiring treatment. Aspiration pneumonia associated mortality ranged from 20% to 65%. Unidentified dysphagia caused significant morbidity, increased mortality, and decreased the quality of life. In this review we underline definition, causes, predictive factors of dysphagia and report on pretreatment and on-treatment evaluation, suggesting some key points to avoid underestimation. A multi-parameter assessment of swallowing problems may allow an earlier diagnosis. An appropriate evaluation might lead to a better treatment of both symptoms and cancer.

show abstract

Section: Resultsmentioning

confidence: 99%

Dysphagia in Head and Neck Cancer Patients: Pretreatment Evaluation, Predictive Factors, and Assessment during Radio-Chemotherapy, Recommendations

Denaro

Merlano

Russi

2013

Clin Exp Otorhinolaryngol

125

102

View full text Add to dashboard Cite

show abstract

“…Randomized clinical trials are the gold standard in treatment efficacy studies. A number of randomized clinical trials have been instituted in the past few years that address some of these issues and may demonstrate the superiority of various therapy procedures in treated head and neck cancer patients [224]. One study funded by the National Institute of Diabetes and Digestive and Kidney Disease compares the effects of the Shaker exercise with range of motion exercise in treated head and neck cancer patients and post-stroke patients.…”

Section: Efficacy Of Swallowing Therapy Procedures For Patients With mentioning

confidence: 99%

Rehabilitation of Dysphagia Following Head and Neck Cancer

Pauloski

2008

Physical Medicine and Rehabilitation Clinics of North America

188

124

View full text Add to dashboard Cite

SYNOPSIS Patients with cancers of the oral cavity, pharynx or larynx may be treated with surgery, radiotherapy, chemotherapy, or a combination of these modalities. Each treatment type may have a negative impact on posttreatment swallowing function; these effects are presented in this chapter. The clinician has a number of rehabilitative procedures available to reduce or eliminate swallowing disorders in patients treated for cancer of the head and neck. The various procedures--including postures, maneuvers, modifications to bolus volume and viscosity, range of motion exercises, and strengthening exercises--and their efficacy in treated head and neck cancer patients are discussed.

show abstract

“…Most dysphagia patients recover within 3 weeks of stroke onset, but a recovery is not guaranteed. It may take a more protracted course and may lead to serious complications, such as pneumonia, malnutrition or even death [4,5,6]. …”

Section: Introductionmentioning

confidence: 99%

The Effect of Early Neuromuscular Electrical Stimulation Therapy in Acute/Subacute Ischemic Stroke Patients With Dysphagia

et al. 2014

View full text Add to dashboard Cite

ObjectiveTo compare the outcome of an early application of neuromuscular electrical stimulation (NMES) combined with traditional dysphagia therapy (TDT) versus traditional dysphagia therapy only in acute/subacute ischemic stroke patients with moderate to severe dysphagia by videofluoroscopic swallowing study (VFSS).MethodsFifty-seven dysphagic stroke patients were enrolled in a VFSS within 10 days after stroke onset. Patients were randomly assigned into two treatment groups. Thirty-one patients received NMES combined with TDT (NMES/TDT group) and 26 patients received TDT only (TDT group). Electrical stimulation with a maximal tolerable intensity was applied on both suprahyoid muscles for 30 minutes, 5 days per week during 3 weeks. The swallowing function was evaluated at baseline and 3, 6, and 12 weeks after baseline. Outcomes of the VFSS were assessed using the Functional Oral Intake Scale (FOIS).ResultsThe mean ages were 63.5±11.4 years in the NMES/TDT group and 66.7±9.5 years in the TDT group. Both groups showed a significant improvement on the FOIS after treatment. The FOIS score was significantly more improved at 3 and 6 weeks after baseline in the NMES/TDT group than in the TDT group (p<0.05).ConclusionAn early application of NMES combined with TDT showed a positive effect in acute/subacute ischemic stroke patients with dysphagia. These results indicated that the early application of NMES could be used as a supplementary treatment of TDT to help rehabilitate acute/subacute dysphagic stroke patients by improving their swallowing coordination.

show abstract

Update on Clinical Trials in Dysphagia

Cited by 28 publications

References 14 publications

Dysphagia in Head and Neck Cancer Patients: Pretreatment Evaluation, Predictive Factors, and Assessment during Radio-Chemotherapy, Recommendations

Dysphagia in Head and Neck Cancer Patients: Pretreatment Evaluation, Predictive Factors, and Assessment during Radio-Chemotherapy, Recommendations

Rehabilitation of Dysphagia Following Head and Neck Cancer

The Effect of Early Neuromuscular Electrical Stimulation Therapy in Acute/Subacute Ischemic Stroke Patients With Dysphagia

Contact Info

Product

Resources

About