Update on endoscopic treatment of Barrett’s oesophagus and Barrett’s oesophagus–related neoplasia

Pech, Oliver; Alqahtani, Saleh A.

doi:10.1177/2631774520935241

Cited by 4 publications

(5 citation statements)

References 34 publications

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“…Finally, our data can help when deciding on the preferred ablation technique. Various new ablation therapies for BE-related neoplasia are currently being evaluated as alternatives to RFA, with some showing promising results [15]. As soon as newly developed ablation techniques match the efficacy and safety of RFA, patient tolerability might become decisive for selection of the preferred technique.…”

Section: Discussionmentioning

confidence: 99%

The course of pain and dysphagia after radiofrequency ablation for Barrett’s esophagus-related neoplasia

et al. 2022

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Background Radiofrequency ablation (RFA) is effective for eradication of Barrett’s esophagus (BE) neoplasia, but little is known on the course of pain and dysphagia after RFA. We aimed to describe the course of post-RFA symptoms and to identify possible associated risk factors. Methods In this multicenter, observational cohort study, all RFA procedures registered in a prospective database were included. Patient and treatment characteristics were collected from medical records and patients self-registered post-procedural symptoms in electronic symptom diaries for 14 days. Mixed model regression was used for the analyses. Results In total, 255 diaries were completed. Post-RFA pain was reported for 95 % (95 %CI 93–98) of procedures (median duration 14 days; 25th–75th percentiles [p25–p75] 11–14) and major pain for 64 % (95 %CI 58–69; median duration 8 days, p25–p75 3–13). Post-procedural pain significantly increased with BE length, younger age, and no prior ablation. Dysphagia was present after 83 % (95 %CI 79–88) of procedures (median duration 13 days, p25–p75 9–14). The risk of dysphagia decreased with age and increased when patients experienced more pain. Conclusions RFA treatment for BE-related neoplasia seems a significant burden for patients, and post-procedural symptoms should be taken into account when counseling patients before starting endoscopic eradication therapy.

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Section: Discussionmentioning

confidence: 99%

The course of pain and dysphagia after radiofrequency ablation for Barrett’s esophagus-related neoplasia

et al. 2022

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“…Для эндоскопического лечения пищевода Барретта все чаще используются технологии на базе современной науки: аргон-плазменная коагуляция (АПК), ультразвуковая деструкция, лазерная и фотодинамическая терапия, радиочастотная и криоабляция, эндоскопическая резекция слизистой оболочки. Аргон-плазменная коагуляция считается одним из самых безопасных и результативных методов с минимальными побочными эффектами и осложнениями [10][11][12].…”

Section: результаты и обсуждениеunclassified

Complex approach in diagnostics and treatment of gastroesophageal reflux disease complicated by metaplasia of the esophagus

Cherkasov¹,

Cherkasov²,

Гаджиевна³

et al. 2022

Medical news of the North Caucasus

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rostov state medical university, rostov-on-Don, russian federationПроанализированы результаты лечения 34 пациентов с гастроэзофагеальной рефлюксной болезнью (ГЭРБ), осложненной метаплазией слизистой оболочки пищевода. У 19 (55,9 %) пациентов выявлена кишечная метаплазия, у 9 (26,5 %) -желудочная метаплазия, в 6 случаях -дисплазия низкой степени на фоне кишечной (4) и желудочной (2) метаплазии. После верификации диагноза, консервативной терапии и антирефлюксной операции выполнялась аргон-плазменная коагуляция в зависимости от максимальной длины циркулярного сегмента метаплазии. Осложнений, связанных с процедурой, отмечено не было. В отдаленном периоде у всех пациентов отмечалась регенерация участков метаплазии здоровой тканью. За 6 лет наблюдений ни у одного больного не выявлено рецидивов. Основой успешного лечения ГЭРБ, осложненной метаплазией слизистой оболочки пищевода, является комплексный подход, а разработанная методика аргон-плазменной коагуляции позволяет избежать стриктур пищевода и добиться регресса метаплазии. Ключевые слова: гастроэзофагельная рефлюксная болезнь, рефлюкс-эзофагит, метаплазия пищевода, пищевод БарреттаThe treatment results of 34 patients with GERD complicated by metaplasia of the esophageal mucosa were analyzed. According to the pathomorphological conclusion, 19 (55.9 %) had intestinal metaplasia, in 9 (26.5 %) founded gastric metaplasia, in the remaining 6 cases -low-grade dysplasia against the background of intestinal (4) and gastric (2) metaplasia. After provided diagnosis verification, conservative therapy and antireflux surgery, the patient underwent argon-plasma coagulation, depended from the maximum length of the circular segment of metaplasia. There were no complications, associated with argon-plasma coagulation procedures. In the long-term period, all patients showed regeneration of metaplasia areas with healthy tissue. In observation during 6 years, there were no patient had a relapse of the disease. The basis for the successful treatment is an integrated approach, and the developed technique of argon-plasma coagulation, that allows to avoid the esophageal strictures and to achieve the regression of metaplasia of the esophageal mucosa.

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“…La técnica resectiva de elección es la RME, aunque debe plantearse DSE en lesiones > 15 mm, o cuando existe dificultad técnica para RME o sospecha de infiltración submucosa (25).…”

Section: Adenocarcinoma Esofágicounclassified

“…Como hemos comentado antes, el riesgo de progresión en EB sin displasia es residual con lo que el tratamiento endoscópico está indicado en EB con displasia de bajo grado, displasia de alto grado y adenocarcinoma mucoso o incluso submucoso sin criterios de mal pronóstico (25).…”

Section: Adenocarcinoma Esofágicounclassified

Radiological diagnosis of invasive breast cancer

Godaracena¹

2022

Rev Cancer

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RESUMENEl cáncer de esófago presenta una incidencia creciente en el mundo occidental, fundamentalmente el adenocarcinoma. Habitualmente se diagnostica por síntomas como disfagia, que se presenta en fases avanzadas de la enfermedad y se asocia a un mal pronóstico, mientras que en este momento no existen estrategias de cribado que hayan demostrado ser coste-efectivas. El diagnóstico endoscópico precoz puede detectar lesiones en sus fases iniciales en las que se puede conseguir un tratamiento eficaz mediante técnicas poco invasivas, mientras que la ecoendoscopia alta representa el método de elección para el estadiaje en cuanto a la infiltración en profundidad (T) o ganglionar locorregional (N), que puede determinar la indicación de abordaje endoscópico, quirúrgico o la necesidad de tratamiento neoadyuvante. Los avances en las técnicas endoscópicas de detección precoz y en tratamientos mínimamente invasivos pueden disminuir la incidencia y la carga de esta enfermedad.PALABRAS CLAVE: Esófago de Barrett. Diagnóstico endoscópico. Ecoendoscopia. Cribado.

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Update on endoscopic treatment of Barrett’s oesophagus and Barrett’s oesophagus–related neoplasia

Cited by 4 publications

References 34 publications

The course of pain and dysphagia after radiofrequency ablation for Barrett’s esophagus-related neoplasia

The course of pain and dysphagia after radiofrequency ablation for Barrett’s esophagus-related neoplasia

Complex approach in diagnostics and treatment of gastroesophageal reflux disease complicated by metaplasia of the esophagus

Radiological diagnosis of invasive breast cancer

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