Update on the diagnosis and treatment of CNO in children: a clinician’s perspective
Clément Triaille,
Jean Jacques De Bruycker,
Marie-Claude Miron
et al.
Abstract:Chronic non-bacterial osteomyelitis (CNO) is caused by aseptic inflammation of bones, primarily driven by the innate immune system. CNO may display different clinical presentations (acute
vs
chronic, uni-
vs
multifocal) and is accompanied by other inflammatory disorders in up to a third of patients. Once considered a rare disorder, it has become clear that many patients were underdiagnosed. With increasing awareness and the development of total-body MRI protocols, … Show more
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