Update on the diagnosis and management of COVID-19 in pediatric patients

Carlotti, Ana P. C. P.; Carvalho, Werther Brunow de; Johnston, Cíntia; Gilio, Alfredo Elias; Marques, Heloísa Helena de Sousa; Ferranti, Juliana Ferreira; Rodriguez, Isadora Souza; Delgado, Artur Figueiredo

doi:10.6061/clinics/2020/e2353

Cited by 18 publications

(41 citation statements)

References 50 publications

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“…Çocuklarda COVID-19 tedavisiyle ilgili yeterli kanıt bulunmamaktadır, daha çok erişkin çalışmalarına göre tedavi protokolleri belirlenmektedir. Klinik tablonun daha hafif seyirli olması ve ilaçların olası yan etkileri de göz önüne alınarak tedavinin her çocuk için ayrı değerlendirilmesi, ağır pnömonisi olan veya risk faktörü olup hafif hastalık geçirenlerde ilaç tedavisi önerilmektedir (7,8).…”

Section: Conflict Of Interestunclassified

Astımlı Çocuklarda COVID-19 Etkisi

Şen

Mısırlıoğlu

2021

Turkish Journal of Pediatric Disease

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Akut şiddetli respiratuar sendrom koronavirüs-2 (SARS-CoV-2) kaynaklı koronavirüs hastalığı 2019 (COVID-19), özellikle akciğerleri tutarak ciddi ve ölümcül sonuçlara neden olabilmektedir. Hastalığın çocuklarda erişkinlere göre daha hafif seyirli olduğu bildirilmiştir, ancak erişkinlerde olduğu gibi çocuklarda da kronik hastalıklar ciddi COVID-19 hastalığı için risk oluşturabilmektedir. Özellikle kronik akciğer hastalıkları risk faktörü olarak kabul edilirken, çocukluk çağında astımın COVID-19 için risk oluşturup oluşturmadığına dair net bir veri henüz yoktur. Bunun yanında, pandemi dönemindeki çevresel, toplumsal ve sağlık sistemindeki değişikliklerin pediyatrik astım hastalarının takibine ve hastalık kontrolüne olumlu ve olumsuz etkileri gözlenmektedir. Bu yazıda, astımlı çocuklarda COVID-19'un etkilerinin belirlenmesi ve bu süreçte pediyatrik astımın yönetimi için literatür gözden geçirilmiştir.

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Section: Conflict Of Interestunclassified

Astımlı Çocuklarda COVID-19 Etkisi

Şen

Mısırlıoğlu

2021

Turkish Journal of Pediatric Disease

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“…COVID-19 disease can be tested using real-time polymerase chain reaction (RT-PCR) tests, serologic methods, and imaging techniques [11,17]. However, RT-PCR is the standard strategy for diagnosing SARS-CoV-2 as it detects the viral attack with a 62% accuracy rate within the first 24 hours after contracting the infection and over the accuracy rate is up to 80% after three days [17]. The testing procedure for conducting the method entails sample collection and extraction [18].…”

Section: Laboratory Findingsmentioning

confidence: 99%

“…Subsequent steps include purification of the virus, PCR amplification, and nucleic acid analysis. Specimens for the method include nasal swabs, sputum, lung fluids, and saliva [17,19].…”

Section: Laboratory Findingsmentioning

confidence: 99%

“…Sample extraction and RNA magnification can be automated or done manually by different technological instruments. The RT-PCR test identifies viral genetic materials upon entering the human body [17].…”

Section: Laboratory Findingsmentioning

confidence: 99%

“…Serologic methods involve investigating antibody response upon detecting SARS-CoV-2 in the body. The virus can be diagnosed using rapid tests and advanced laboratory techniques [17]. Serologic methods should be used limitedly since there are concerns over their accuracy and pathogen specificity.…”

Section: Laboratory Findingsmentioning

confidence: 99%

See 2 more Smart Citations

COVID-19: The Pediatric Perspective

Basalom

Ismail

Sindi

et al. 2021

JPRI

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Since the appearance of the novel corona virus disease 19 (COVID-19) from Wuhan in China, there have been a lot of researches to uncover the hidden clues that may help in eliminating the outbreak. In a short period of time, the disease has infected millions of people around the globe and was declared as a pandemic by the world health organization (WHO). Different subgroups of the community have been studied and reports have described the course of the disease among pregnant ladies, elders, immunodeficient patients and patients with chronic diseases. However, this review aimed at describing the novel COVID-19 among children and adolescents. The review discusses the prevalence, symptoms, diagnostic investigations, management, and the role of pharmacotherapy of COVID-19. In general, children have a milder course of diseases compared to adults. The symptoms include fever, diarrhea, abdominal pain, cough, fatigue, and other non-specific symptoms. The diagnosis is usually made with a serological test of a body fluid sample from saliva or nose. The role of radiography in the forms of chest X-ray and computed tomography (CT) is not of great benefit to the children. For mild presentations of the disease among children, the management is mainly supportive and there is no indication for antiviral therapy or specific pharmacotherapy except for fever lowering agents like Paracetamol. In terms of prevention, children aged 12 or more can be vaccinated for the objective of preventing the spread of infection, inducing antibody release, and shortening the recovery period.

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Laboratory methods: A concise review and update for COVID‐19 diagnosis

Nemati

Jafari

Ebrahimi

et al. 2023

Cell Biochemistry & Function

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Since late December 2019, coronavirus disease 2019 (COVID‐19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been rapidly spread across the globe. The early, safe, sensitive, and accurate diagnosis of viral infection is required to decrease and control contagious infection and improve public health surveillance. The diagnosis generally is made by detecting SARS‐CoV‐2‐related agents, including a range of nucleic acid detection‐based, immunoassay‐based, radiographic‐based, and biosensor‐based methods. This review presents the progress of various detection tools for diagnosing COVID‐19 and addresses the advantages and restrictions of each detection method. Given that diagnosis of a contagious various like SARS‐COV‐2 can improve patient survival rates and break the transmission chain, there is no surprise that significant efforts should be made to reduce the limitations of tests that lead to false‐negative results and to develop a substantial test for COVID‐19 diagnosis.

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Update on the diagnosis and management of COVID-19 in pediatric patients

Cited by 18 publications

References 50 publications

Astımlı Çocuklarda COVID-19 Etkisi

Astımlı Çocuklarda COVID-19 Etkisi

COVID-19: The Pediatric Perspective

Laboratory methods: A concise review and update for COVID‐19 diagnosis

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