Update on the use of corticosteroids in third molar surgery: systematic review of the literature

Evaluation of effects of two dexamethasone formulations in impacted third molar surgeries

“…Impacted third molar extraction is in general associated to moderate to severe postoperative discomfort, even when the technique is subtly used, as shown in figure 4, which shows higher painful sensitivity in the periods of 4, 12 and 24h after the procedure [1][2][3]10 . There is a broad discussion about the best drug to minimize postoperative discomfort in dentistry and among the best drugs of choice, dexamethasone is being evaluated by several scientific studies due to its efficacy to control inflammatory complications as compared to its non-use [5][6][7] .…”

“…These postoperative pathophysiological events are associated to the release of inflammatory mediators resulting from arachidonic acid metabolism, which may bring discomfort to patients and affect their quality of life [1][2][3] . Several professionals have emphasized the need for better controlling the postoperative inflammatory process of such surgical procedures, and different drugs have been proposed for such.…”

Pulsed electromagnetic fields for postoperative pain: a randomized controlled clinical trial in patients undergoing mandibular third molar extraction

“…[38][39][40] Corticosteroids and NSAIDs are commonly prescribed to control pain and inflammation after third molar surgery (narcotic analgesics and NSAIDs for pain, and glucocorticoids for swelling and trismus). 41,42 Combining the use of analgesic medication with or other forms of pain relief to achieve cumulative or synergistic effects is the goal of the so-called multimodal pain management or analgesia. 43 When this concept is extended to wearable devices, PEMF therapy may be seen as an adjunct to pain medication with a view to improving pain relief, reducing the need for painkillers in order to contain side effects, or both.…”

Best Practices for Management of Pain, Swelling, Nausea, and Vomiting in Dentoalveolar Surgery

“…The administration of corticosteroids in the preoperative period via the parenteral route has the greatest impact on reducing postoperative swelling and trismus. 28 Comparing corticosteroid administration versus NSAIDs for the relief of pain, swelling, and trismus has also been studied. The preemptive intravenous administration of tenoxicam (NSAID) was compared with the intravenous administration of methylprednisolone on pain, swelling, and trismus after wisdom teeth extraction.…”