Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma

Kudsieh, Bachar; Fernández‐Vigo, José Ignacio; Flores‐Moreno, Ignacio; Ruiz‐Medrano, Jorge; García-Zamora, María; Samaan, Muhsen; Ruiz-Moreno, José M.

doi:10.3390/jcm12072592

Cited by 3 publications

(2 citation statements)

References 82 publications

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“…It is consistently located at the outer margin of the myopic conus [1][2][3]5,17]. It is correlated with myopic tilted disc and posterior staphyloma [4,39]. All cases of Freund's series exhibited fundus complications of severe myopia [1].…”

Section: Association Of Picc With Other Myopia-related Changesmentioning

confidence: 98%

Peripapillary Intrachoroidal Cavitation

Ehongo

Bacq

2023

JCM

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Peripapillary intrachoroidal cavitation (PICC) is a yellow-orange lesion, located at the outer border of the myopic conus. First described as a localized detachment of the retinal pigment epithelium, its intrachoroidal location was later revealed, justifying its current name. PICC is related to other myopic complications such as posterior staphyloma, but its pathogenesis is not clear to date. Although it has been considered a benign condition, most eyes with PICC show visual field defects, which leads to diagnostic uncertainty as these deficits resemble those seen in glaucoma. Furthermore, eyes with PICC may develop macular detachment with retinoschisis. Finally, misdiagnosis of PICC as a metastatic choroidal tumor may lead to unnecessary and anxiety-inducing investigations. Advances in optical coherence tomography (OCT) imaging have improved the visualization of ocular structures, contributing to the understanding of PICC. Recently, high optic nerve sheath traction forces during eye movements in highly myopic eyes have been suggested as promoters of PICC, renewing interest around this condition. However, a review of PICC is still lacking. Therefore, we aimed to provide a concise yet comprehensive overview of the current state of the art, focusing on OCT illustrations, pathophysiology and potential future perspectives based on the biomechanics of the optic nerve.

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Section: Association Of Picc With Other Myopia-related Changesmentioning

confidence: 98%

Peripapillary Intrachoroidal Cavitation

Ehongo

Bacq

2023

JCM

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“…By scanning the laser beam in the X and Y directions, 3D morphological images of the sample are obtained. OCT is already in wide clinical use in ophthalmology to help in the diagnosis and treatment of various eye pathologies [19,20]. It is now being explored for applications within the field of otolaryngology, commonly known as Ear, Nose, and Throat [21].…”

Section: Introductionmentioning

confidence: 99%

Automated Segmentation of Optical Coherence Tomography Images of the Human Tympanic Membrane Using Deep Learning

Oghalai,

Long,

Kim

et al. 2023

Algorithms

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Optical Coherence Tomography (OCT) is a light-based imaging modality that is used widely in the diagnosis and management of eye disease, and it is starting to become used to evaluate for ear disease. However, manual image analysis to interpret the anatomical and pathological findings in the images it provides is complicated and time-consuming. To streamline data analysis and image processing, we applied a machine learning algorithm to identify and segment the key anatomical structure of interest for medical diagnostics, the tympanic membrane. Using 3D volumes of the human tympanic membrane, we used thresholding and contour finding to locate a series of objects. We then applied TensorFlow deep learning algorithms to identify the tympanic membrane within the objects using a convolutional neural network. Finally, we reconstructed the 3D volume to selectively display the tympanic membrane. The algorithm was able to correctly identify the tympanic membrane properly with an accuracy of ~98% while removing most of the artifacts within the images, caused by reflections and signal saturations. Thus, the algorithm significantly improved visualization of the tympanic membrane, which was our primary objective. Machine learning approaches, such as this one, will be critical to allowing OCT medical imaging to become a convenient and viable diagnostic tool within the field of otolaryngology.

show abstract

Peripapillary Intrachoroidal Cavitation

Ehongo¹,

Bacq²

2023

Preprint

View full text Add to dashboard Cite

Peripapillary intrachoroidal cavitation (PICC) is a yellow-orange lesion, located at the outer border of the myopic conus. First described as a localized detachment of the retinal pigment epithelium, its intrachoroidal location was later disclosed, justifying its current name. PICC is related to other myopic complications like posterior staphyloma, but its pathogenesis is not clear to date. Although it has been considered a benign condition, most eyes with PICC show visual field defects, leading to diagnostic uncertainty as these deficits resemble those observed in glaucoma. Furthermore, eyes with PICC can develop macular detachment with retinoschisis. Finally, misdiagnosis of PICC as a metastatic choroidal tumor may lead to unnecessary and anxiety-provoking investigation. Advances in optical coherence tomography (OCT) imaging have improved the visualization of ocular structures, contributing to the understanding of PICC. Recently high optic nerve sheaths traction forces during eye movements in highly myopic eyes have been suggested as promoters of PICC, renewing interest around this condition. However, a review of PICC is still lacking. Therefore, we aimed to provide a concise yet comprehensive overview of the current state of the art, focusing on OCT documentation, pathophysiology and potential future perspectives based on biomechanics of the optic nerve.

show abstract

Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma

Cited by 3 publications

References 82 publications

Peripapillary Intrachoroidal Cavitation

Peripapillary Intrachoroidal Cavitation

Automated Segmentation of Optical Coherence Tomography Images of the Human Tympanic Membrane Using Deep Learning

Peripapillary Intrachoroidal Cavitation

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