This article provides information on the types of plant bugs, their damage, and measures to combat them in cotton agrobiocenoses of Uzbekistan. As a result of the conducted research, 15 species of bugs, of which Eurystylus bellevoyei (Reuter, 1879) species were identified for the first time in the cotton fields of Uzbekistan. In special experiments in the cages, it was determined that when 100-150 bugs correspond to 100 cotton plants during the vegetation stage of the cotton plant, cotton yield decreases to 32.3-36.4% owing to the effect of alfalfa bug (Adelphocoris lineolatus) and 8.6-13.5% owing to the plant bug (Lygus. protensis). If cotton is infected with a cotton shredder bug (Creontiades pallidus) in the early period (June), the yield of cotton decreases from 61.6% to 88.9%, if there are 30 to 150 plant bugs per 100 cotton plants. If it is infected later (July-August), the yield of cotton decreases from 38.0 to 50.2%. If fine fiber cotton is damaged by bugs (100-150 specimens per 100 cotton plants) during the vegetation stage, the cotton yield will decrease by 55.5-65.3% compared to the control variant. The most effective drugs against plant bugs are: Safegor, 40% (98.3%), Ribo Super, 25% (93.4%), Transform, 50% (92.5%), and Mosetam 20 (82.8-81.9%). Arvilmek 1.8 (active substance- abamectin), Lead, 5% (substance-pymetrozine), Imido Star, 20% (imidacloprid) were found to have unsatisfactory (below 70.0%) results against cotton bugs.