Updates in Parkinson’s Disease Integrative Therapies: an Evidence-Based Review

Kola, Sushma; Subramanian, Indu

doi:10.1007/s11910-023-01312-z

Cited by 2 publications

(1 citation statement)

References 92 publications

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“…Also little attention is paid to people with advanced PD (including cognitive impairment), to overall costs and long-term effects. In addition to these existing models, several physical exercise programs (e.g., dancing, climbing, music therapy), or adjunct tools (e.g., virtual reality and robotics), are offered as add-on treatments [24][25][26][27][28][29][30][31][32]. A Cochrane report on the effect of physical exercise for PwPD, including 156 randomized controlled trials (RCTs) with a total of 7,939 participants, concluded that most types of physical exercise improved the movement patterns and quality of life, whereas the efficacy of these types of physical exercise did not show significant differences.…”

Section: Overview Of Pd Inpatient Rehabilitation Data Before 2020mentioning

confidence: 99%

The Effectiveness of Inpatient Rehabilitation in Parkinson’s Disease: A Systematic Review of Recent Studies

Steendam-Oldekamp,

van Laar

2024

Journal of Parkinson’s Disease

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Background: Parkinson’s disease (PD) is a progressive disease, which is associated with the loss of activities of daily living independency. Several rehabilitation options have been studied during the last years, to improve mobility and independency. Objective: This systematic review will focus on inpatient multidisciplinary rehabilitation (MR) in people with Parkinson’s disease (PwPD), based on recent studies from 2020 onwards. Methods: Search strategy in three databases included: multidisciplinary rehabilitation, Parkinson’s Disease, inpatient rehabilitation, motor-, functional- and cognitive performance, cost-effectiveness, Quality of Life, and medication changes/Levodopa equivalent daily doses. Results: Twenty-two studies were included, consisting of 13 studies dealing with inpatient MR and 9 studies on inpatient non-MR interventions. Inpatient PD multidisciplinary rehabilitation proved to be effective, as well as non-MR rehabilitation. Conclusions: This review confirms the efficacy of inpatient MR and non-MR in PD, but is skeptical about the past and current study designs. New study designs, including new physical training methods, more attention to medication and costs, new biomarkers, artificial intelligence, and the use of wearables, will hopefully change rehabilitation trials in PwPD in the future.

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Section: Overview Of Pd Inpatient Rehabilitation Data Before 2020mentioning

confidence: 99%

The Effectiveness of Inpatient Rehabilitation in Parkinson’s Disease: A Systematic Review of Recent Studies

Steendam-Oldekamp,

van Laar

2024

Journal of Parkinson’s Disease

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Towards multimodal cognition-based treatment for cognitive impairment in Parkinson's disease: drugs, exercise, non-invasive brain stimulation and technologies

Mantovani,

Bressan,

Tinazzi

et al. 2024

Current Opinion in Neurology

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Purpose of review Cognitive impairment is one of the most challenging non-motor symptoms of Parkinson's disease (PD) and may occur during all PD stages. There are no established pharmacological treatments for PD-related cognitive impairment, which may be improved by cognition-based interventions (i.e., cognitive stimulation, cognitive training, cognitive rehabilitation). Multimodal cognition-based interventions by adjunctive drugs, exercise, non-invasive brain stimulation and technologies may be effective in PD. Recent findings Exercise combined with cognitive training may enhance global, memory, visuospatial and executive functioning, transcranial direct current stimulation delivered alongside cognitive training may improve attention and executive functioning, and exergames, semi-immersive virtual reality (VR) and telerehabilitation plus non-immersive VR combined with cognitive training may ameliorate global and executive functioning in PD patients. Summary The evidence reviewed here, despite preliminary, is very encouraging and suggests strong rationale for combining pharmacological and non-pharmacological interventions with cognition-based treatments in PD. To overcome limitations of current studies, we propose some recommendations for future trials on drugs, exercise, non-invasive brain stimulation and technologies combined with cognition-based treatments for cognitive impairment in PD.

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Updates in Parkinson’s Disease Integrative Therapies: an Evidence-Based Review

Cited by 2 publications

References 92 publications

The Effectiveness of Inpatient Rehabilitation in Parkinson’s Disease: A Systematic Review of Recent Studies

The Effectiveness of Inpatient Rehabilitation in Parkinson’s Disease: A Systematic Review of Recent Studies

Towards multimodal cognition-based treatment for cognitive impairment in Parkinson's disease: drugs, exercise, non-invasive brain stimulation and technologies

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