Updates on an At-Risk Population: Late-Preterm and Early-Term Infants

Stewart, Dan L.; Barfield, Wanda D.; Newborn,

doi:10.1542/peds.2019-2760

Cited by 95 publications

(68 citation statements)

References 59 publications

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“…Although few of these UTx deliveries were pursued electively, it is necessary to consider that infants born in the late preterm period (from 34 0/7 weeks to 36 6/7 weeks gestation) and the early term period (from 37 0/7 weeks to 38 6/7 weeks gestation) exhibit higher rates of mortality and lifelong morbidities than full-term infants born from 39 0/7 weeks to 40 6/7 weeks gestation. 13 Specifically, late preterm and early term infants are at risk of impaired growth, learning disabilities, behavioral disturbances, and psychiatric disorders that extend into school age and beyond. [14][15][16][17] Frequency of follow-up and type of assessment after hospital For this reason, several members of the USUTC are actively working with UNOS and the appropriate professional societies to ensure that the data will be properly collected and scientifically reported.…”

Section: Offspring Reporting Recommendationsmentioning

confidence: 99%

“…However, it is important to note that the mean gestational age of these infants was 34 6/7 weeks, with a maximum gestational age of 37 0/7 weeks. Although few of these UTx deliveries were pursued electively, it is necessary to consider that infants born in the late preterm period (from 34 0/7 weeks to 36 6/7 weeks gestation) and the early term period (from 37 0/7 weeks to 38 6/7 weeks gestation) exhibit higher rates of mortality and lifelong morbidities than full‐term infants born from 39 0/7 weeks to 40 6/7 weeks gestation 13 . Specifically, late preterm and early term infants are at risk of impaired growth, learning disabilities, behavioral disturbances, and psychiatric disorders that extend into school age and beyond 14‐17 …”

Section: Outcome Measuresmentioning

confidence: 99%

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Guidelines for standardized nomenclature and reporting in uterus transplantation: An opinion from the United States Uterus Transplant Consortium

Johannesson

Testa

Flyckt

et al. 2020

American Journal of Transplantation

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Uterus transplantation is a nascent but growing field. To support this growth, the United States Uterus Transplant Consortium proposes guidelines for nomenclature related to operative technique, vascular anatomy, and donor, recipient, and offspring outcomes. In terms of anatomy, the group recommends reporting donor arterial inflow and recipient anastomotic site delivering inflow to the graft and offers standardization of the names for the 4 veins originating from the uterus because of current inconsistency in this particular nomenclature. Seven progressive stages with milestones of success are defined for reporting on uterus transplantation outcomes: (1) technical, (2) menstruation, (3) embryo implantation, (4) pregnancy, (5) delivery, (6) graft removal, and (7) long-term follow-up. The 3 primary metrics for success are recipient survival (as reported for other organ transplant recipients), graft survival, and uterus transplant live birth rate (defined as live birth per transplanted recipient). A number of secondary outcomes should also be reported, most of which capture stage-specific milestones, as well as data on graft failure. Outcome metrics for living donors include patient survival, survival free of operative intervention, and data on complications and hospitalizations. Finally, we make specific recommendations on follow-up for offspring born from uterine grafts, which includes specialty surveillance as well as collection and reporting of routine pediatric outcomes. The goal of standardization in reporting is to create consistency and improve the quality of evidence available on the efficacy and value of the procedure.

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Section: Offspring Reporting Recommendationsmentioning

confidence: 99%

Section: Outcome Measuresmentioning

confidence: 99%

Guidelines for standardized nomenclature and reporting in uterus transplantation: An opinion from the United States Uterus Transplant Consortium

Johannesson

Testa

Flyckt

et al. 2020

American Journal of Transplantation

View full text Add to dashboard Cite

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“…The neonatal observations we encountered have been well described for other populations born at similar gestational ages. 16 The median birth weight was 2,920 g, 74th percentile. One of 12 infants born was small for gestational age, and one was large for gestational age (infants: 10 and 9).…”

Section: Discussionmentioning

confidence: 96%

Neonatal Outcomes after Uterus Transplantation: Dallas Uterus Transplant Study

et al. 2021

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Objective Limited data are available on the outcome of infants born after uterus transplantation. Our aim was to describe the hospital course and laboratory findings in the first 2 months of life of the 12 infants born in the Dallas UtErus Transplant Study (DUETS). Study Design Based on the trial protocol, information about infants was collected in a prospective fashion, including infant demographics, hospital course, and laboratory values. Results Twelve infants were delivered, all by cesarean section, from 11 mothers who had undergone uterus transplantation (one mother had two pregnancies and delivered two babies). All pregnancies were singleton. The mothers received immunosuppressive therapy, and one had a rejection episode that was detected during pregnancy. The rejection episode resolved after steroid treatment. The infants had a median gestational age of 366/7 weeks (range: 306/7–380/7 weeks) and median birth weight of 2,920 g (range: 1,770–3,470 g). The lowest Apgar's score at 5 minutes was 8. All infants were appropriate size for gestational age. Two infants presented with bandemia but negative blood cultures. At 2 months of age, all infants achieved the developmental and behavioral milestones outlined by the American Academy of Pediatrics. Conclusion The 12 infants born from mothers with uterus transplants had a neonatal course that reflected the gestational age at delivery. No baby was born with an identified malformation or organ dysfunction. Longer follow-up and a larger number of infants are needed to confirm these observations. Key Points

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“…Late preterm (34 + 0 -36 + 6 weeks' gestation) and early term births (37 + 0 -38 + 6 weeks' gestation) respectively constitute 3-6% and 15-31% of single live births across high-income countries [1]. A combined proportion of these two populations are secondary to full term births (39 + 0 -41 + 6 weeks' gestation) [2].…”

Section: Introductionmentioning

confidence: 99%

Higher risk for poor handwriting in Taiwanese children born late preterm

Hwang¹,

Chih-Cheng²,

Shih³

et al. 2021

Preprint

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BackgroundLate preterm and early term births constitute a significant proportion of live births. However, handwriting skills of these two populations remain unclear. We aimed to investigate their risk for poor Chinese handwriting in grade two.MethodsA total of 185 second graders born late preterm (34+ 0-36+ 6 weeks gestation, n = 54), early term (37+ 0-38+ 6 weeks gestation, n = 56), and full term (39+ 0-41+ 6 weeks gestation, n = 75) without any intervention or diagnosis related to developmental delays were included. Their handwriting performance was rated by teachers using the Chinese Handwriting Evaluation Form (CHEF), which is a standardized handwriting scale including five handwriting dimensions (construction, accuracy, directionality, speed, and pencil grasp).ResultsAfter controlling for demographic risk factors, the late preterm born group had a greater risk of having worse performance in the full form (adjusted odds ratio < OR > = 3.93; p = .038) and construction dimension (adjusted OR = 4.77; p = .009) of the CHEF than peers born at full term; whereas the risks were comparable for the early and full term born groups.ConclusionsLate preterm but not early term born children were found to be at higher risk for poor Chinese handwriting in grade two. They particularly have difficulty with spatial construction including size, spacing, and alignment of Chinese characters and components that may influence handwriting legibility.

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Updates on an At-Risk Population: Late-Preterm and Early-Term Infants

Cited by 95 publications

References 59 publications

Guidelines for standardized nomenclature and reporting in uterus transplantation: An opinion from the United States Uterus Transplant Consortium

Guidelines for standardized nomenclature and reporting in uterus transplantation: An opinion from the United States Uterus Transplant Consortium

Neonatal Outcomes after Uterus Transplantation: Dallas Uterus Transplant Study

Higher risk for poor handwriting in Taiwanese children born late preterm

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