2020
DOI: 10.1097/01.hj.0000669900.75620.75
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Updates on Auditory Neuropathy Spectrum Disorder

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“…Arnold Starr et al, in 1996, identified for the first time hearing loss resulting from disorder of the auditory portion of the vestibulocochlear nerve, called auditory neuropathy (AN), characterized by abnormal neural conduction of acoustic signals in the presence of normal sensory transduction and preserved outer hair cell amplification properties [Colucci, 2020]. It leads to presence of otoacoustic emissions (OAE) and/or cochlear microphonism and absence or abnormal auditory brainstem responses and acoustic reflexes [Starr et al, 1996;Sarankumar et al, 2018].…”
Section: Introductionmentioning
confidence: 99%
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“…Arnold Starr et al, in 1996, identified for the first time hearing loss resulting from disorder of the auditory portion of the vestibulocochlear nerve, called auditory neuropathy (AN), characterized by abnormal neural conduction of acoustic signals in the presence of normal sensory transduction and preserved outer hair cell amplification properties [Colucci, 2020]. It leads to presence of otoacoustic emissions (OAE) and/or cochlear microphonism and absence or abnormal auditory brainstem responses and acoustic reflexes [Starr et al, 1996;Sarankumar et al, 2018].…”
Section: Introductionmentioning
confidence: 99%
“…It leads to presence of otoacoustic emissions (OAE) and/or cochlear microphonism and absence or abnormal auditory brainstem responses and acoustic reflexes [Starr et al, 1996;Sarankumar et al, 2018]. Although the exact sites of AN lesions remain unknown, studies have suggested sites such as ribbon pre-synapses of inner hair cells; postsynaptic region of unmyelinated dendrites in the auditory nerve; postsynaptic disorders affecting auditory ganglion cells, as well as their myelinated axons and dendrites; and central neural pathway disorders affecting the auditory brainstem [Starr et al, 1996;Colucci, 2020].…”
Section: Introductionmentioning
confidence: 99%