Upper airway multilevel radiofrequency under local anesthesia can improve CPAP adherence for severe OSA patients

Emara, Tarek Abdelzaher; Ibrahim, Huda; Elmalt, Ashraf E.; Dahy, Khaled G.; Rashwan, Mohamed S.

doi:10.1016/j.amjoto.2022.103671

Cited by 4 publications

(3 citation statements)

References 19 publications

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“…Recently, the results of several studies showed that radiofrequency treatment has significant success in the reduction of snoring but limited use for treating OSA [ 76 , 77 , 78 , 79 ]. However, another study also showed that radiofrequency tissue reduction significantly improves the tolerance and adherence of severe OSA patients using CPAP [ 80 ].…”

Section: Surgical Therapy For Obstructive Sleep Apneamentioning

confidence: 99%

Oromaxillofacial Surgery: Both a Treatment and a Possible Cause of Obstructive Sleep Apnea—A Narrative Review

Martinović

Tokic

Puizina-Mladinic

et al. 2023

Life

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Obstructive sleep apnea (OSA) is a chronic, sleep-related breathing disorder. It is characterized by a nocturnal periodic decrease or complete stop in airflow due to partial or total collapse of the oropharyngeal tract. Surgical treatment of OSA is constantly evolving and improving, especially with the implementation of new technologies, and this is needed because of the very heterogeneous reasons for OSA due to the multiple sites of potential airway obstruction. Moreover, all of these surgical methods have advantages and disadvantages; hence, patients should be approached individually, and surgical therapies should be chosen carefully. Furthermore, while it is well-established that oromaxillofacial surgery (OMFS) provides various surgical modalities for treating OSA both in adults and children, a new aspect is emerging regarding the possibility that some of the surgeries from the OMFS domain are also causing OSA. The latest studies are suggesting that surgical treatment in the head and neck region for causes other than OSA could possibly have a major impact on the emergence of newly developed OSA, and this issue is still very scarcely mentioned in the literature. Both oncology, traumatology, and orthognathic surgeries could be potential risk factors for developing OSA. This is an important subject, and this review will focus on both the possibilities of OMFS treatments for OSA and on the OMFS treatments for other causes that could possibly be triggering OSA.

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Section: Surgical Therapy For Obstructive Sleep Apneamentioning

confidence: 99%

Oromaxillofacial Surgery: Both a Treatment and a Possible Cause of Obstructive Sleep Apnea—A Narrative Review

Martinović

Tokic

Puizina-Mladinic

et al. 2023

Life

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“…La reducción tisular multinivel por radiofrecuencia de la vía aérea superior mejora la tolerancia y la adherencia de los pacientes con AOS grave que utilizan CPAP después de la cirugía (35). Una fórmula predictiva basada en AHI, IMC, LAT y minSpO2 es útil para calcular la CPAP efectiva para pacientes con SAOS moderado a grave en China (36).…”

Section: Avances Tecnológicos Y Los Enfoques Terapéuticos Innovadores...unclassified

Actualización sobre la Terapia de Presión Positiva Continua en las Vías Respiratorias como Tratamiento del Síndrome de Apnea del Sueño

Minchala León,

Encalada Torres

2023

Salud ConCienc.

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Introducción: la Apnea Obstructiva del Sueño (AOS) se caracteriza por episodios recurrentes de colapso parcial o total de las vías respiratorias superiores durante el sueño, la prevalencia en adultos entre 54 a 93 años superaba el 60%, con una AOS de moderada a grave en el 30,3% de los individuos de etnia blanca, el 32,4% de afroamericanos, 38,2% de hispanos y el 39,4% de ascendencia china. Objetivo: Describir la actualización sobre la terapia de presión positiva continua en las vías respiratorias como tratamiento del síndrome de apnea del sueño. Metodología: se realizó una revisión bibliográfica tipo narrativa, los estudios fueron recogidos de diferentes bases de datos como Medline, Lilacs, TripDataBase, Cochrane Library, Epistemonikos, Scopus, mediante identificación-cribado-elegibilidad-selección y basado en el rango de calidad de Scimago Journal Rank. Resultados: se encontraron múltiples efectos del tratamiento, se demostró mejoras significativas en la somnolencia y calidad de vida. También se observó un impacto positivo en la depresión y ligera mejora en las funciones neurocognitivas. Además, mostró beneficios en la prevención de accidentes cerebrovasculares y fibrilación auricular. La adherencia al CPAP se vio influenciada por factores socioeconómicos, psicológicos y efectos secundarios de las mascarillas. Estos hallazgos sugieren la eficacia y la relevancia del tratamiento con CPAP en pacientes con AOS, así como la importancia de considerar múltiples factores para mejorar la adherencia y los resultados del tratamiento.

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“…Repeated hypoxic events and concomitant sleep disruption cause ventilatory instability, oxidative stress, inflammation, and disruption of vascular function [5]. The gold-standard treatment for OSAHS is a device that provides continuous pressure on the upper airway, called continuous positive airway pressure (CPAP), which can correct intermittent hypoxemia, reduce vascular endothelial dysfunction, and decreases ventilatory responsiveness to hypoxia [6]. Moreover, CPAP has a consistent ancillary effect, which includes intermittent hypercapnia, sleep fragmentation, repetitive increases in negative intrathoracic pressure, sympathetic nerve activity surge, and blood pressure (BP) [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of continuous positive airway pressure on TNF-α in obstructive sleep apnea patients: A meta-analysis

Luo

Zhang

et al. 2023

PLoS ONE

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Background Tumor necrosis factor-α (TNF-α) is an important mediator of the immune response. At present, the improvement of TNF-α after continuous positive airway pressure (CPAP) treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) is still controversial. Methods We conducted a systematic review of the present evidence based on a meta-analysis to elucidate the effects of TNF-α on OSAHS after CPAP treatment. Results To measure TNF-α, ten studies used enzyme-linked immunosorbent assay (ELISA), and one used radioimmunoassay. The forest plot outcome indicated that CPAP therapy would lower the TNF-α levels in OSAHS patients, with a weighted mean difference (WMD) of 1.08 (95% CI: 0.62–1.55; P < 0.001) based on the REM since there is highly significant heterogeneity (I2 = 90%) among the studies. Therefore, we used the subgroup and sensitivity analyses to investigate the source of heterogeneity. The findings of the sensitivity analysis revealed that the pooled WMD ranged from 0.91 (95% CI: 0.52–1.31; P < 0.001) to 1.18 (95% CI: 0.74–1.63; P < 0.001). The findings were not influenced by any single study. Notably, there was homogeneity in the Asia subgroup and publication year: 2019, implying that these subgroups could be the source of heterogeneity. Conclusion Our meta-analysis recommends that CPAP therapy will decrease the TNF-α level in OSAHS patients, but more related research should be conducted.

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Upper airway multilevel radiofrequency under local anesthesia can improve CPAP adherence for severe OSA patients

Cited by 4 publications

References 19 publications

Oromaxillofacial Surgery: Both a Treatment and a Possible Cause of Obstructive Sleep Apnea—A Narrative Review

Oromaxillofacial Surgery: Both a Treatment and a Possible Cause of Obstructive Sleep Apnea—A Narrative Review

Actualización sobre la Terapia de Presión Positiva Continua en las Vías Respiratorias como Tratamiento del Síndrome de Apnea del Sueño

Efficacy of continuous positive airway pressure on TNF-α in obstructive sleep apnea patients: A meta-analysis

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