Upper airway symptoms in primary snoring and in sleep apnea

Kreivi, Hanna-Riikka; Virkkula, Paula; Lehto, Juho T.; Brander, Pirkko

doi:10.3109/00016489.2011.644803

Cited by 16 publications

(21 citation statements)

References 20 publications

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“…5,6 In support of the link between nasal inflammation and OSA in children, our data identified a high prevalence of rhinitis in children with overnight PSG-confirmed OSA (43%), which is similar to what has been previously described in adult studies. 24 The presence of rhinitis did not correlate with OSA severity according to standard PSG parameters (OAHI and OSA-related SaO 2 desaturation) in our retrospective pediatric cohort. These findings are in general agreement with prior data reported in adults.…”

Section: Discussionmentioning

confidence: 94%

“…9 Another large study (524 subjects mean Ϯ SD; aged 51 Ϯ 12 years) established that nasal symptoms are highly prevalent in subjects with PSGconfirmed diagnosis of OSA: 54% had nasal stuffiness and 33% reported sneezing. 24 Interestingly, despite the fact that rhinitis and OSA are very common in children, 10 a recent systematic review of existing literature over the last 25 years identified only 18 articles on the association between these two conditions in the pediatric population. 10 Only six studies (33%) included cases with OSA confirmed by overnight PSG, the gold standard for this disorder in children.…”

Section: Discussionmentioning

confidence: 99%

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The Link between Rhinitis and Rapid-Eye-Movement Sleep Breathing Disturbances in Children with Obstructive Sleep Apnea

Huseni

Gutiérrez

Rodríguez‐Martínez

et al. 2014

Am J Rhinol�Allergy

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

The Link between Rhinitis and Rapid-Eye-Movement Sleep Breathing Disturbances in Children with Obstructive Sleep Apnea

Huseni

Gutiérrez

Rodríguez‐Martínez

et al. 2014

Am J Rhinol�Allergy

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“…In OSAS patients, during apnea periods, brain oxygenation is further decreased [57,58]. e brain is sensitive to oxygen level in the blood and tissue [59,60].…”

Section: Discussionmentioning

confidence: 99%

“…Workers with daytime sleepiness should be evaluated for Obstructive Sleep Apnea Syndrome (OSAS), and polisomnographic examination should be conducted (57,58). In OSAS patients, during apnea periods, brain oxygenation is further decreased [57,58].…”

Section: Discussionmentioning

confidence: 99%

Effects of long-term low-level solvent exposure on cognitive function

Saygun

Ekici²,

Muluk³

et al. 2012

CIM

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TurkeyE ects of long-term low-level solvent exposure on cognitive function Abstract Purpose: e e ects of long-term low-level exposures to solvents on cognitive function were investigated.Methods: A total of 389 workers at a gun factory, those exposed to solvents (n=193) and those that were not exposed to solvents during work (n=196), were included. All the workers were given a questionnaire. Cognitive function was evaluated by Mini-mental Status Examination (MMSE) and psychological status was assessed by Hospital Anxiety and Depression (HAD) Scale. Results:No di erences were found in the MMSE and HAD scores between solventexposed workers and control workers (p>0.05). In the workers who had used a mask for a longer time, orientation scores were lower. Daytime sleepiness was related to lower recall scores.. Le -handed workers had higher total HAD scores than right-handed workers.Conclusions: Long-term low-level exposure to solvents did not a ect cognitive function in the workers, according to their MMSE scores. Duration of solvent exposure was also not related to MMSE Scores. Short sleep duration and daytime sleepiness may negatively a ect cognitive function.

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“…16 The adverse effects of CPAP therapy are local mainly to the upper airways but may cause patients substantial discomfort, 5,6,8,17 even leading to treatment cessation. This study confirms one of our previous findings, 8 that CPAP treatment alleviates mouth dryness in OSA subjects.…”

Section: Discussionmentioning

confidence: 99%

Persistence of Upper-Airway Symptoms During CPAP Compromises Adherence at 1 Year

2016

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BACKGROUND:The most common adverse effects of CPAP are related to the upper airways. We evaluated upper-airway symptoms before and after a CPAP trial as well as their effect on CPAP adherence. We also evaluated the effect of humidification added to CPAP therapy on upper-airway symptoms. METHODS: We followed for 1 y 536 subjects with obstructive sleep apnea scheduled consecutively for CPAP initiation. Subjects completed visual analog questionnaires on nasal stuffiness, rhinorrhea, and mouth dryness (0 ‫؍‬ no symptoms, 100 ‫؍‬ severe symptoms). RESULTS: Before CPAP initiation, mean nasal stuffiness score was 29.6 ؎ 24.9, rhinorrhea score was 16.0 ؎ 21.7, and mouth dryness score was 43.8 ؎ 33.1. In subjects who quit CPAP treatment before the 1-y follow-up, the increase in rhinorrhea score during CPAP initiation was significant, 5.3 (95% CI 0.5-9.5, P ‫؍‬ .02), and in those using CPAP at 1 y, nasal stuffiness score and mouth dryness score decreased significantly during initiation, ؊5.1 (95% CI ؊7.9 to ؊2.4, P < .001) and ؊21.2 (؊25.5 to ؊17.4, P < .001). Mouth dryness score decreased significantly with CPAP regardless of humidification: change with humidification, ؊18.1 (95% CI ؊22.1 to ؊14.3), P < .001; change without, ؊10.5 (95% CI ؊16.9 to ؊4.1), P ‫؍‬ .002. Humidification also prevented the aggravation of rhinorrhea (change, ؊0.4 [95% CI ؊2.6 to 1.9], P ‫؍‬ .75) and alleviated nasal stuffiness (change ؊5.3 [95% CI ؊7.8 to ؊2.6], P < .001) with CPAP, whereas its absence induced a significant rise in symptom scores: change in rhinorrhea, 11.5 (95% CI 7.1-16.7), P < .001; change in nasal stuffiness, 8.5 (95% CI 3.9 -13.5, P < .001). CONCLUSIONS: The severity of upper-airway symptoms before CPAP does not predict CPAP use at 1 y, whereas CPAP non-users at 1 y had smaller or no alleviation in symptom scores during initiation compared with those who continued CPAP treatment.

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Upper airway symptoms in primary snoring and in sleep apnea

Cited by 16 publications

References 20 publications

The Link between Rhinitis and Rapid-Eye-Movement Sleep Breathing Disturbances in Children with Obstructive Sleep Apnea

The Link between Rhinitis and Rapid-Eye-Movement Sleep Breathing Disturbances in Children with Obstructive Sleep Apnea

Effects of long-term low-level solvent exposure on cognitive function

Persistence of Upper-Airway Symptoms During CPAP Compromises Adherence at 1 Year

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