Upper Gastrointestinal Bleeding Caused by Severe Esophagitis: A Unique Clinical Syndrome

Guntipalli, Prathima; Chason, Rebecca D.; Elliott, Alan C.; Rockey, Don C.

doi:10.1007/s10620-014-3258-4

Cited by 17 publications

(12 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Upper digestive bleeding was present in 297 (9.88%) of cases with esophagitis. The prevalence is very similar to a study in America, which describes a ratio of 7.85%, with a higher incidence in men [15].…”

Section: Discussionsupporting

confidence: 87%

Comparative study of Clinical Characteristics in Patients with Mild and Severe Reflux Esophagitis

Macarie

Băţagă

Pantea

et al. 2020

Acta Marisiensis - Seria Medica

View full text Add to dashboard Cite

Objective: This study aims to determine the correlation between risk factors and erosive esophagitis development.Methods: We conducted a retrospective observational study on a consecutive series of 19.672 patients who underwent upper gastrointestinal endoscopy between 01.01.2011-31.12.2017. A total of 3005 patients, diagnosed with erosive esophagitis, were included in the present study and stratified according to Los Angeles classification.Results: During the studied period we found 3005 patients with erosive esophagitis, sex ratio male to female was 1.3/1, the most common forms of esophagitis being grade A and B: 74.54% patients with esophagitis grade A, 14.80% patients with grade B; 5.29% patients were with grade C and 5.35% patients with esophagitis grade D. In severe esophagitis the male predominance was more prevalent (249 males, 71 female), with a sex ratio 3.50/1. The correlation of male gender with severe esophagitis was highly statistically significant (p < 0.0001, OR 2.97; 95% CI 2.25-3.91). Hiatal hernia was diagnosed in 1171 patients, the presence of large hiatal hernias, being an important predictor, with statistical significance (p < 0.0001, OR 3.41; 95% CI 2.22-5.21), for severe esophagitis development. Incidence of Helicobacter pylori infection was 11.51%, in the entire study group, with no statistical significant difference between patients with mild or severe esophagitis (12.02% vs 7.18%).Conclusion: Erosive esophagitis is a frequent disease, the most common forms being grade A and B. Male gender and the presence of hiatal hernia are the most important risk factors for erosive esophagitis development, in our study group.

show abstract

Section: Discussionsupporting

confidence: 87%

Comparative study of Clinical Characteristics in Patients with Mild and Severe Reflux Esophagitis

Macarie

Băţagă

Pantea

et al. 2020

Acta Marisiensis - Seria Medica

View full text Add to dashboard Cite

show abstract

“…Alcohol decreases the lower esophageal sphincter tone and inhibits peristalsis of the esophagus, resulting in an increase and prolongation of gastroesophageal reflux [10]. A study on GI bleeding caused by esophagitis demonstrated lower mortality and rebleeding rate in patients with esophagitis versus other bleeding etiology; however, the effect of alcohol use was not investigated [21]. In contrast, another study of 213 patients with mortality from gastroesophageal reflux disease showed that alcohol abuse increased the risk of death from hemorrhagic esophagitis, which was the cause of death in many (n = 82) of the study patients [22].…”

Section: Discussionmentioning

confidence: 99%

Alcohol Abuse Increases Rebleeding Risk and Mortality in Patients with Non-variceal Upper Gastrointestinal Bleeding

et al. 2015

View full text Add to dashboard Cite

show abstract

“…In patients with UGIB secondary to esophagitis, hematemesis is more common than melena. 7 The presence of associated odynophagia and dysphagia will depend on the chronicity and severity of the underlying condition.…”

Section: Esophagitismentioning

confidence: 99%

Upper Gastrointestinal Bleeding: Etiologies and Management

Kamboj

Hoversten

Leggett

2019

Mayo Clinic Proceedings

120

View full text Add to dashboard Cite

Upper Gastrointestinal Bleeding Caused by Severe Esophagitis: A Unique Clinical Syndrome

Abstract: We have described a unique clinical syndrome in patients with upper gastrointestinal bleeding who have erosive esophagitis. This syndrome is manifest by typical clinical features and is associated with favorable outcomes.

Cited by 17 publications

References 17 publications

Comparative study of Clinical Characteristics in Patients with Mild and Severe Reflux Esophagitis

Comparative study of Clinical Characteristics in Patients with Mild and Severe Reflux Esophagitis

Alcohol Abuse Increases Rebleeding Risk and Mortality in Patients with Non-variceal Upper Gastrointestinal Bleeding

Upper Gastrointestinal Bleeding: Etiologies and Management

Contact Info

Product

Resources

About