2015
DOI: 10.1016/j.jvs.2015.01.026
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Upper limb vascular calcification score as a predictor of mortality in diabetic hemodialysis patients

Abstract: Diabetic hemodialysis patients exposed to high levels of upper extremity arterial medial VcSs upon receiving RCFs have an increased long-term mortality risk compared with diabetic hemodialysis patients with no Vc and receiving the same access. Patients with CVCs/Vc had the lowest survival rates.

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Cited by 16 publications
(21 citation statements)
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“…VC often begins early and gets severe during the course of CKD, particularly in individuals with DM. This explains why the prevalence, extent, and progression of VC as well as the incidence of CVE are higher in diabetics with concomitant CKD [7,8,9].…”
Section: Introductionmentioning
confidence: 99%
“…VC often begins early and gets severe during the course of CKD, particularly in individuals with DM. This explains why the prevalence, extent, and progression of VC as well as the incidence of CVE are higher in diabetics with concomitant CKD [7,8,9].…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, a mechanism involved could be worsening of Windkessel effect, because of increased arterial rigidity and decreased vascular elasticity, which impairs tissue perfusion due to VC 24,43 . In addition, vascular mineralization may act as an adjunct etiology of this process or even in its progression 44,45 , adding importance to this study. Nonetheless, we did not find glomerular calcification in ob/ob mice, but we cannot rule out the hypothesis that decreased tissue perfusion and increased BMP-2 expression could have impacted in glomerular dysfunction, by altering podocytes number and/or function [46][47][48] and increasing inflammation 19,49 .…”
Section: 26mentioning
confidence: 99%
“…While there is an increasing number of studies that sustain the clinical benefits of cell therapies in coronary artery disease and lower limb ischemia, [70][71][72][73][74][75] there are scarce data on their role in upper limb ischemia, which is rarer, but if present, is associated with significantly worse outcomes and increased mortality rates. 76,77 There is a whole body of evidence on the beneficial effects of different cell therapies in lower limb PAD, 78 but there are few data on the effect of angiogenesis stimulation in upper limb ischemia. However, there are reports of several cases with critical ischemia of the upper limb that have benefited from BMSC as an angiogenic inducer.…”
Section: Upper Limb Ischemiamentioning
confidence: 99%