2020
DOI: 10.3390/jcm9092845
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Upper Respiratory Tract Microbiome and Otitis Media Intertalk: Lessons from the Literature

Abstract: Otitis media (OM) is one of the most common diseases occurring during childhood. Microbiological investigations concerning this topic have been primarily focused on the four classical otopathogens (Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes) mainly because most of the studies have been conducted with culture-dependent methods. In recent years, the introduction of culture-independent techniques has allowed high-throughput investigation of entire bacterial … Show more

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Cited by 15 publications
(7 citation statements)
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“…OME can occur after a known or unrecognized spell of acute otitis media. OME is associated with conductive hearing loss (median 25 dB) 12 . OME functional effect is conductive loss of hearing, which is believed to impair speech, language, and cognitive development.…”
Section: Discussionmentioning
confidence: 99%
“…OME can occur after a known or unrecognized spell of acute otitis media. OME is associated with conductive hearing loss (median 25 dB) 12 . OME functional effect is conductive loss of hearing, which is believed to impair speech, language, and cognitive development.…”
Section: Discussionmentioning
confidence: 99%
“…In pediatric healthcare, mastoiditis presents a significant concern as the most common complication of otitis media, impacting both immediate management and long-term implications [6]. Understanding the microbial etiology, as revealed by studies examining bacterial flora in otitis media, provides crucial insights into managing mastoiditis effectively [7]. A three-step treatment approach is proposed as follows: initial conservative measures with antibiotics, followed by ear drainage if needed, and antro-mastoidectomy as a definitive option if conservative measures fail [8].…”
Section: Introductionmentioning
confidence: 99%
“…Changes in the oral or nasopharyngeal microbiota can contribute to the development of various conditions; these alterations have been associated with an increased risk of several pathologies such as otitis media and secretory otitis media [ 7 ]. Otitis media with effusion is caused by fluid accumulation in the middle ear behind the tympanic membrane, without a clear clinical presentation suggesting acute inflammation.…”
Section: Introductionmentioning
confidence: 99%