2022
DOI: 10.21203/rs.3.rs-1363952/v1
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Upregulation of hsa_circ_0002003 Promotes Hepatocellular Carcinoma Progression

Abstract: Background Circular RNAs (circRNAs), which are involved in various human malignancies, have emerged as promising biomarkers. The present study aimed to investigate unique expression profiles of circRNAs in hepatocellular carcinoma (HCC) and identify novel biomarkers associated with HCC development and progression. Methods CircRNA expression profiles of HCC tissues were jointly analyzed to identify differentially expressed circRNAs. Overexpression plasmid and siRNA targeting candidate circRNAs were used in fu… Show more

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