Upregulation of Specific mRNA Levels in Rat Brain After Cell Phone Exposure

Abstract

Adult Sprague-Dawley rats were exposed to regular cell phones for 6 h per day for 126 days (18 weeks). RT-PCR was used to investigate the changes in levels of mRNA synthesis of several injury-associated proteins. Calcium ATPase, Neural Cell Adhesion Molecule, Neural Growth Factor, and Vascular Endothelial Growth Factor were evaluated. The results showed statistically significant mRNA up-regulation of these proteins in the brains of rats exposed to cell phone radiation. These results indicate that relative chronic exposure to cell phone microwave radiation may result in cumulative injuries that could eventually lead to clinically significant neurological damage.

Assessing elementary understanding of electromagnetic radiation and its implementation in wireless technologies among pre-service teachers

“…As artificial sources of electromagnetic radiation, such as wireless networks and cell phones, have become a part of people's daily lives (Kumar et al, 2011;Piper et al, 2019;Salehan & Negahban, 2013), education should provide individuals with the requisite knowledge and encourage critical thinking so they can make informed decisions about their safety (International Commission on Non-Ionizing Radiation Protection, 2009). Researchers have raised serious concerns about the potential impact of prolonged exposure to electromagnetic radiation on living organisms (Baste et al, 2008;Carlberg & Hardell, 2012;Hepworth et al, 2006;Levitt & Lai, 2010;Lonn et al, 2005;Yan et al, 2009). It is thus important to prioritize development of critical thinking skills among individuals through education, as demonstrated by numerous studies.…”

Effect of radio-frequency electromagnetic radiations (RF-EMR) on passive avoidance behaviour and hippocampal morphology in Wistar rats

“…Ginkgo biloba significantly prevented these changes in the brain (21). Exposure of adult Sprague-Dawley rats to regular cell phones resulted in mRNA up-regulation of several injury-associated proteins, such as calcium ATPase, neural cell adhesion molecule, neural growth factor, and vascular endothelial growth factor (22). The possible role of programmed cell death in the brain could also not to be excluded.…”

Spatial Memory Perfomance of Wistar Rats Exposed to Mobile Phone

“… 11 Exposure of adult Sprague-Dawley rats to regular cell phones resulted in mRNA up-regulation of several injury-associated proteins such as calcium ATPase, neural cell adhesion molecules, neural growth factor, and vascular endothelial growth factor. 12 A study in guinea pigs has shown an increase in MDA and decrease in GSH levels and catalase activity in brain tissue after exposure to 890 to 915-MHz RF from a cellular phone. 13 …”