Upstaging of basal cell and squamous cell carcinomas during definitive surgery: a review of predictive preoperative clinical and histologic features

Clements, Stephanie; Khachemoune, Amor

doi:10.1007/s00403-020-02151-5

Cited by 5 publications

(1 citation statement)

References 24 publications

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“…This procedure is preferred because an infiltrative histology may sometimes be present only at the deeper, advancing margins of a tumor, and superficial biopsies will frequently miss this component. 52,53 After BCC diagnosis, a full skin examination is recommended, because individuals with skin cancer often have additional, concurrent precancers or cancers located at other, usually sun-exposed skin sites. These individuals are also at increased risk of developing cutaneous melanoma.…”

Section: Clinical Presentation and Workupmentioning

confidence: 99%

Basal Cell Skin Cancer, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology

Schmults,

Blitzblau,

Aasi

et al. 2023

Journal of the National Comprehensive Cancer Network

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Basal cell carcinoma (BCC) is the most common form of skin cancer in the United States. Due to the high frequency, BCC occurrences are not typically recorded, and annual rates of incidence can only be estimated. Current estimated rates are 2 million Americans affected annually, and this continues to rise. Exposure to radiation, from either sunlight or previous medical therapy, is a key player in BCC development. BCC is not as aggressive as other skin cancers because it is less likely to metastasize. However, surgery and radiation are prevalent treatment options, therefore disfigurement and limitation of function are significant considerations. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) outline an updated risk stratification and treatment options available for BCC.

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Section: Clinical Presentation and Workupmentioning

confidence: 99%