Uptake, bioaccumulation, biodistribution and depuration of polystyrene nanoplastics in zebrafish (Danio rerio)

Habumugisha, Théogène; Fang, Cheng; Yan, Changzhou; Zhang, Xian

doi:10.1016/j.scitotenv.2023.164840

Cited by 17 publications

(2 citation statements)

References 110 publications

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“…11,12 Therefore, more attention should be paid to the risk of NPs in the environment. 13 Now, some studies have been focused on the ecological effects of NPs. For example, it was found that PSN may bio-magnify through trophic transfer since carboxylated PSN have been reported to accumulate in the intestine of several aquatic species, including brine shrimp ( Artemia franciscana ) and sea urchin embryos ( Paracentrotus lividus ).…”

Section: Introductionmentioning

confidence: 99%

Qualitative and quantitative analysis of accumulation and biodistribution of polystyrene nanoplastics in zebrafish (Danio rerio) via artificial freshwater

Habumugisha,

Zhang,

Ndayishimiye

et al. 2023

Environ. Sci.: Nano

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Section: Introductionmentioning

confidence: 99%

Qualitative and quantitative analysis of accumulation and biodistribution of polystyrene nanoplastics in zebrafish (Danio rerio) via artificial freshwater

Habumugisha,

Zhang,

Ndayishimiye

et al. 2023

Environ. Sci.: Nano

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“…It is well-documented that NPs have predominately accumulated in the aquatic organism’s intestinal tract, including zebrafish, rainbow trout (Oncorhynchus mykiss), sea urchins (Strongylocentrotus intermedius), and D. magna. − There is a growing number of studies that have associated NPs exposure with impaired intestinal health effects in fish . Tilapia (Oreochromis niloticus)-administered NPs induced epithelial damage in the intestine and impaired intestinal permeability, suggesting that ingested NPs can impair the physical barrier of the gut in fish .…”

Section: Introductionmentioning

confidence: 99%

Caught in Fish Gut: Uptake and Inflammatory Effects of Nanoplastics through Different Routes in the Aquatic Environment

Wang,

Qiu,

Cheng

et al. 2023

ACS EST Water

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The global impact of nanoplastics (NPs) as emerging pollutants on water environments remains uncertain. Previous studies have focused on the toxicity of NPs itself, often ignoring the important effects of exposure routes. Here, we evaluated the impact of different exposure routes (waterborne, foodborne, and coexposure) of 80 nm polystyrene NPs on intestinal accumulation and inflammatory response using zebrafish. Our results demonstrated that aqueous and dietary exposures led to both time-and dose-dependent bioaccumulation of NPs, damaged intestinal structure, and induced immune cells and genes in the intestine. While waterborne exposure caused lower NPs accumulation than foodborne exposure, both demonstrated similar immunotoxicity in the intestine. In addition, co-exposure can lead to a higher accumulation of NPs and toxicity in zebrafish, suggesting that the risk of environmental exposure may be underestimated, as current toxicity assessments have focused on single-route exposure scenarios. We further revealed that NPs activated downstream genes of the toll-like 4 receptor, suggesting that NPs can cause an inflammatory response. Our study is the first known to report that exposure to NPs via different routes induces an accumulation in the intestine and can cause similar intestinal disturbance effects, providing new insights for adequately assessing the potential risks of NPs.

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Uptake, removal and trophic transfer of fluorescent polyethylene microplastics by freshwater model organisms: the impact of particle size and food availability

Gong,

Wang,

Wang

et al. 2024

Aquatic Toxicology

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Uptake, bioaccumulation, biodistribution and depuration of polystyrene nanoplastics in zebrafish (Danio rerio)

Cited by 17 publications

References 110 publications

Qualitative and quantitative analysis of accumulation and biodistribution of polystyrene nanoplastics in zebrafish (Danio rerio) via artificial freshwater

Qualitative and quantitative analysis of accumulation and biodistribution of polystyrene nanoplastics in zebrafish (Danio rerio) via artificial freshwater

Caught in Fish Gut: Uptake and Inflammatory Effects of Nanoplastics through Different Routes in the Aquatic Environment

Uptake, removal and trophic transfer of fluorescent polyethylene microplastics by freshwater model organisms: the impact of particle size and food availability

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