1966
DOI: 10.1159/000211552
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Uptake of S<sup>35</sup>-Methionine and S<sup>35</sup>-Chondroitin Sulphate by the Carrageenin Granuloma in Rats of Different Ages

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“…
It has been observed before that the S35-sulphate uptake of carragee nin granuloma is greater in young than in adult rats [16], whereas the S35-Chondroitin sulphate uptake is the same in both age groups [15]. Therefore it is not the binding of preformed acid mucopolysaccharides (AMPS) but their synthesis in the granuloma that is changed by ageing, as has been indicated also in the literature [13].
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confidence: 83%
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“…
It has been observed before that the S35-sulphate uptake of carragee nin granuloma is greater in young than in adult rats [16], whereas the S35-Chondroitin sulphate uptake is the same in both age groups [15]. Therefore it is not the binding of preformed acid mucopolysaccharides (AMPS) but their synthesis in the granuloma that is changed by ageing, as has been indicated also in the literature [13].
…”
mentioning
confidence: 83%
“…The granuloma were produced by the subcutaneous injection of carrageenin solution containing 8.5 g% sulphur, as in our earlier experiment [15]. A total of 118 male rats, divided into three age groups, were used: (1) 42 'weanlings', 4-5 weeks of age, average weight 100 g; (2) 36 'young' rats (3-4 months of age, average weight 182 g); (3) 40 'adult' rats (8-9 months of age, average weight 290 g).…”
Section: Aterials and Methodsmentioning
confidence: 99%