2022
DOI: 10.4103/jcrt.jcrt_28_20
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Urachal adenocarcinoma

Abstract: The urachus is a canal between the allantois and the early fetal bladder. Urachal carcinoma is a rare and aggressive type of bladder cancer. This cancer usually presents at an advanced stage. We report a 70-year-old patient with malignant transformation of urachal cyst several years later. The patient was treated with partial cystectomy and adjuvant radiotherapy. A review of the published literature is also presented.

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Cited by 12 publications
(7 citation statements)
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“…About 8 % of patients are asymptomatic, 15 and when symptomatic urachal adenocarcinomas present with haematuria, mucinuria, palpable mass, bacteriuria, umbilical or pelvic pain and weight loss. 9 , 14 , 15 , 19 Diagnosing urachal carcinoma accurately is difficult due to its histologic similarities with other adenocarcinomas and its close proximity to the bladder and colorectum. It necessitates a careful clinico-pathologic correlation and adherence to specific diagnostic criteria in order to establish a definitive diagnosis.…”
Section: Discussionmentioning
confidence: 99%
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“…About 8 % of patients are asymptomatic, 15 and when symptomatic urachal adenocarcinomas present with haematuria, mucinuria, palpable mass, bacteriuria, umbilical or pelvic pain and weight loss. 9 , 14 , 15 , 19 Diagnosing urachal carcinoma accurately is difficult due to its histologic similarities with other adenocarcinomas and its close proximity to the bladder and colorectum. It necessitates a careful clinico-pathologic correlation and adherence to specific diagnostic criteria in order to establish a definitive diagnosis.…”
Section: Discussionmentioning
confidence: 99%
“…17 CEA and CA19-9 levels increase in these patients due to their histopathological features similar to the enteric epithelium. 19 Elevated serum CA 125 levels can also be observed in certain patients with abdominal carcinomatosis. 20 The prognosis for individuals with urachal adenocarcinoma is typically unfavorable due to the tumor's location, delayed symptom development, and high likelihood of metastasis.…”
Section: Discussionmentioning
confidence: 99%
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