Urachal cancer: Role of conservative surgery

Henly, David R.; Farrow, George M.; Zincke, Horst

doi:10.1016/0090-4295(93)90526-g

Cited by 142 publications

(128 citation statements)

References 15 publications

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“…The prognostic importance of differentiating urachal from nonurachal tumors is unclear in the published literature, as the reported 5-year survival rates are 27% to 61% for urachal [2][3][4][5][6][7] and 11% to 55% for nonurachal tumors. 2,3,[7][8][9] In 1 of the larger series reporting on both types, there was a trend toward improved survival in subjects with urachal adenocarcinoma, although it did not reach statistical significance (P ¼ .07).…”

Section: Discussionmentioning

confidence: 89%

“…Others have described the advanced presentation of urachal tumors and high risk of metastases, 4,6,19 and this presentation may be due to tumor growth that primarily occurs beneath the urothelium in the muscularis or deeper structures of the urachus. 3 This location may lead to a delay in diagnosis, allowing the tumor more time to grow and disseminate before becoming clinically apparent.…”

Section: Discussionmentioning

confidence: 99%

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Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder

Wright¹,

Porter²,

Li³

et al. 2006

Cancer

172

170

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Background The National Institute for Occupational Safety and Health (NIOSH) conducted a health hazard evaluation (HHE) of a water‐damaged school in New Orleans (NO), Louisiana. Our aim in this evaluation was to document employee health effects related to exposure to the water‐damaged school, and to determine if VCS testing could serve as a biomarker of effect for occupants who experienced adverse health effects in a water‐damaged building. Methods NIOSH physicians and staff administered a work history and medical questionnaire, conducted visual contrast sensitivity (VCS) testing, and collected sticky‐tape, air, and dust samples at the school. Counting, culturing, and/or a DNA‐based technology, called mold‐specific quantitative PCR (MSQPCR), were also used to quantify the molds. A similar health and environmental evaluation was performed at a comparable school in Cincinnati, Ohio which was not water‐damaged. Results Extensive mold contamination was documented in the water‐damaged school and employees (n = 95) had higher prevalences of work‐related rashes and nasal, lower respiratory, and constitutional symptoms than those at the comparison school (n = 110). VCS values across all spatial frequencies were lower among employees at the water‐damaged school. Conclusions Employees exposed to an extensively water‐damaged environment reported adverse health effects, including rashes and nasal, lower respiratory, and constitutional symptoms. VCS values were lower in the employees at the water‐damaged school, but we do not recommend using it in evaluation of people exposed to mold. Am. J. Ind. Med. 55:844–854, 2012. This article is a U.S. Government work and is in the public domain in the USA.

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Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder

Wright¹,

Porter²,

Li³

et al. 2006

Cancer

172

170

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“…1 Currently, there are less than 350 cases of urachal cancer reported in the English-language medical literature with most of them being case descriptions. Several of these reports have associated urachal cancer with poor prognosis.…”

mentioning

confidence: 99%

Predictors of survival from urachal cancer

Molina

Quevedo

Furth

et al. 2007

Cancer

Self Cite

149

164

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Objective Antineutrophil cytoplasmic antibody–associated vasculitis (AAV) is characterized by necrotizing vessel wall inflammation, paralleled by the detachment of endothelial cells. The repair of such endothelial defects is crucial for the maintenance of regular structure and function of the injured vessels. Bone marrow–derived endothelial progenitor cells (EPCs) are thought to play a pivotal role in the regeneration of damaged endothelium. The aim of this study was to investigate whether EPCs are involved in vascular repair in AAV. Methods We assessed disease activity, CD34+ hematopoietic progenitor cells (HPCs) using flow cytometry, EPCs using an in vitro assay, and circulating endothelial cells (CECs) by immunomagnetic isolation from the peripheral blood of 31 patients with active AAV at 1, 3, and 6 months after the initiation of immunosuppressive therapy. Results In patients with untreated active disease, HPC and EPC numbers were comparable with those in healthy control subjects (n = 64). With the induction of remission, the number of HPCs and EPCs increased significantly, from a median of 1.5 cells/μl (range 0.0–7.0) to a median of 3.2 cells/μl (range 0.76–9.2) (P < 0.001) and from a median of 261 cells/high‐power field (range 171–643) to a median of 470 cells/high‐power field (range 168–996) (P < 0.021), respectively. In contrast, the initially elevated number of CECs decreased significantly (P < 0.001). We observed no correlation between the number of HPCs or EPCs and the leukocyte count, the thrombocyte count, or kidney function. Conclusion In patients with AAV, the numbers of circulating CD34+ HPCs and EPCs increased significantly after the institution of immunosuppressive therapy and disease remission. This finding points to a role of circulating CD34+ HPCs and EPCs in endothelial repair in vasculitis. Targeted stimulation of these cells might represent a new possibility of improving vascular healing in AAV.

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“…El síntoma más frecuente es la hematuria, debido a la erosión de la cúpula vesical 5,6 . Otros síntomas como la disuria, dolor en hipogastrio o moco en la orina, son menos frecuentes 6,7 . Este tipo de tumores se extienden por el espacio de Retzius, la pared abdominal anterior y el peritoneo 4 .…”

Section: Discussionunclassified

Adenocarcinoma Mucinoso de Uraco y Pseudomixoma Peritoneal

Delgado

Márquez

Solís

et al. 2006

Actas Urológicas Españolas

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RESUMENADENOCARCINOMA MUCINOSO DE URACO Y PSEUDOMIXOMA PERITONEAL. MUCINOUS ADENOCARCINOMA OF THE URACHUS AND PERITONEAL PSEUDOMYXOMA. El adenocarcinoma de uraco es un tumor extremadamente raro, con una incidencia de 1/5.000.000 de habitantes, lo que representa menos del 0,001 de todos los tumores de vejiga.El pseudomixoma peritoneal es una neoplasia rara caracterizada por ascitis mucinosa que envuelve la superficie peritoneal y el omento. Usualmente está asociada con tumores mucinosos benignos o malignos del apéndice u ovario.En este trabajo, presentamos un caso de pseudomixoma peritoneal causado por un adenocarcinoma mucinoso de uraco.Palabras Clave. Adenocarcinoma Mucinoso. Uraco. Pseudomixoma Peritoneal. ABSTRACT AB MUCINOUS ADENOCARCINOMA OF THE URACHUS AND PERITONEAL PSEUDOMYXOMAThe adenocarcinoma of the urachus is very rare tumor, with an incidence of 1/5.000.000 inhabitants, represents less than 0,001 of all types of bladder cancer.Peritoneal pseudomixoma is a rare neoplasm characterized by mucinous acites that involvement the peritoneal surface and omentum. Usually is associated with benign o malignant mucinous tumor of the appendix or ovary.In this paper, we present a case of peritoneal pseudomixoma caused by a mucinous adenocarcinoma of the urachus.

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Urachal cancer: Role of conservative surgery

Cited by 142 publications

References 15 publications

Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder

Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder

Predictors of survival from urachal cancer

Adenocarcinoma Mucinoso de Uraco y Pseudomixoma Peritoneal

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