China faces unprecedented air pollution today. In this study, a database (SO 2 , NO 2 , CO, O 3 , PM 2.5 (particulate matter with aerodynamic diameter less than 2.5 µm), and PM 10 (particulate matter with aerodynamic diameter less than 10 µm) was developed from recordings in 188 cities across China in 2014 and 2015 to explore the spatial-temporal characteristics, relationships among atmospheric contaminations, and variations in these contaminants. Across China, the results indicated that the average monthly concentrations of air pollutants were higher from November to February than in other months. Further, the spatial patterns of air pollutants showed that the most polluted areas were located in Shandong, Henan, and Shanxi provinces, and the Beijing-Tianjin-Hebei region. In addition, the average daily concentrations of air pollutants were also higher in spring and winter, and significant relationships between the principal air pollutants (negative for O 3 and positive for the others) were found. Finally, the results of a generalized additive model (GAM) indicated that the concentrations of PM 10 and O 3 fluctuate dynamically; there was a consistent increase in CO and NO 2 , and PM 2.5 and SO 2 showed a sharply decreasing trend. To minimize air pollution, open biomass burning should be prohibited, the energy efficiency of coal should be improved, and the full use of clean fuels (nuclear, wind, and solar energy) for municipal heating should be encouraged from November to February. Consequently, an optimized program of urban development should be highlighted.