Energy and environmental challenges are a major concern across the world and the urban residential building sector, being one of the main stakeholders in energy consumption and greenhouse gas emissions, needs to be more energy efficient and reduce carbon emissions. While it is easier to design net zero energy homes, existing home stocks are a major challenge for energy retrofitting. Two key challenges are determining the extent of retrofitting required, and developing knowledge-based effective policies that can be applied en-masse to housing stocks and neighborhoods. To overcome these challenges, it is essential to gather critical data about qualities of existing buildings including their age, geo-location, construction type, as well as electro-mechanical and occupancy parameters of each dwelling. The objective of this study was to develop a GIS-based model embedded with critical data of residential buildings to facilitate evidence-based retrofit programs for urban neighborhoods. A model based on a bottom-up approach was proposed in which information gathered from all stakeholders was inputted into one database that can be used for decision-making. A geo-located case study to validate a proposed GIS-based residential retrofitting model sample size of 74 residential buildings in the city of Riyadh was statistically analyzed and used. The results indicate behavior-based patterns, with a strong positive correlation (r = 0.606) between the number of occupants and number of household appliances, while regression analysis showed high occupancy rates do not necessarily result in high utility costs at the end of the month, and there is no statistical difference in the average monthly cost of gas between partial and fully occupied houses. Furthermore, neither the type of building, height, age, nor occupancy status play a significant role in the average energy consumed. Additionally, the GIS-based model was validated and found to be effective for energy-use mapping and gathering critical data for analyzing energy consumption patterns at neighborhood scale, making it useful for municipalities to develop effective policies aimed at energy efficient and smart neighborhoods, based on a recommended list of most effective energy-saving retrofit measures.