Land Surface Temperature (LST) is a key parameter for the estimation of urban fluxes as well as for the assessment of the presence and strength of the surface urban heat island (SUHI). In an urban environment, LST depends on the way the city has been planned and developed over time. To this end, the estimation of LST needs adequate spatial and temporal data at the urban scale, especially with respect to land cover/land use. The present study is divided in two parts: at first, satellite data from MODIS-Terra 8-day product (MOD11A2) were used for the analysis of an eighteen-year time series (2001)(2002)(2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010)(2011)(2012)(2013)(2014)(2015)(2016)(2017) of the LST spatial and temporal distribution in five major cities of the Mediterranean during the summer months. LST trends were retrieved and assessed for their statistical significance. Secondly, LST values and trends for each city were examined in relation to land cover characteristics and patterns in order to define the contribution of urban development and planning on LST; this information is important for the drafting of smart urbanization policies and measures. Results revealed (a) positive LST trends in the urban areas especially during nighttime ranging from +0.412 • K in Marseille to +0.923 • K in Cairo and (b) the SUHI has intensified during the last eighteen years especially during daytime in European Mediterranean cities, such as Rome (+0.332 • K) and Barcelona (+0.307 • K).Surface urban heat island (SUHI), in particular, describes the land surface temperature (LST) differences between urban areas and their surroundings, and it is usually studied with the use of remote sensing data. The formation of SUHI can be mainly attributed to the increased absorption and trapping of solar radiation in urban areas associated with limited release of heat due to the low values of the thermal emission coefficients of manmade materials. Anthropogenic heat release from transport and the heating-cooling systems of the buildings further exacerbate the phenomenon [18][19][20]. Both UHI and SUHI can be detected throughout the year, but they are of particular public policy concern during the summer, because higher surface and air temperatures are associated with increases in electricity demand for air conditioning, air pollution, and heat stress-related mortality and illness [21][22][23][24][25]. Several SUHI studies have been performed in the Mediterranean area, most of them revealing that higher UHI intensities are found in the summer period [13,[26][27][28][29][30].Land surface temperature is a controlling factor for most of the physical, chemical and biological processes on the earth, and can be considered as a measure of climate change [31][32][33][34]. For the urban environment, LST is an important parameter for the monitoring of the energy exchange between the land surface and the atmosphere in terms of the sensible and latent heat fluxes [35][36][37][38] which are important when discussing the thermal effects of the cities on th...