Urethritis Without Skin Lesions as the Primary Manifestation of Mpox Virus Infection

Liesenborghs, Laurens; Huyst, Veerle; Dijck, Christophe Van; Rutgers, Jojanneke; Baetselier, Irith De; Kenyon, Chris; Esbroeck, Marjan Van; Vercauteren, Koen

doi:10.1016/j.eururo.2022.12.022

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“…In France, the intra‐familial transmission of mpox virus was reported 40 . In Belgium, the primary symptom of mpox virus infection was urethritis without skin lesions 41 . Multiple PCR‐positive samples have been reported in asymptomatic individuals 42 .…”

Section: Type Sample Mpox Strain Used Referencesmentioning

confidence: 99%

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Mpox virus Clade IIb detection in the air

Saied

2023

Journal of Medical Virology

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Mpox is a viral zoonotic disease endemic in Central and West Africa that is caused by the Mpox virus, which belongs to the Orthopoxvirus genus and Poxviridae family. The clinical manifestations of mpox infection are milder than those of smallpox, and the incubation time of mpox varies from 5 to 21 days. Since May 2022, the mpox outbreak (formerly known as monkeypox) has suddenly and unexpectedly spread in non-endemic countries, suggesting that there may have been some undetected transmissions. Based on molecular analysis, there are two major genetic clades that represent the mpox virus: Clade I (formerly the Congo Basin clade OR the Central African clade) and Clade II (formerly the West African clade). It is believed that people who are asymptomatic or paucisymptomatic may spread the mpox virus. Infectious viruses cannot be distinguished by PCR testing; therefore, virus culture should be carried out. Recent evidence regarding the detection of the mpox virus (Clade IIb) in air samples collected from the patient's environment during the 2022 mpox outbreak was reviewed. Further studies are needed to evaluate the extent to which the presence of mpox virus DNA in the air could affect immunocompromised patients in healthcare facilities, and further epidemiological studies are crucial, especially in Africa.

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Section: Type Sample Mpox Strain Used Referencesmentioning

confidence: 99%

“…40 In Belgium, the primary symptom of mpox virus infection was urethritis without skin lesions. 41 Multiple PCR-positive samples have been reported in asymptomatic individuals. 42 It is believed that people who are asymptomatic or paucisymptomatic may spread the mpox virus.…”

mentioning

confidence: 99%

Mpox virus Clade IIb detection in the air

Saied

2023

Journal of Medical Virology

View full text Add to dashboard Cite

show abstract

Urethritis Without Skin Lesions as the Primary Manifestation of Mpox Virus Infection

Cited by 1 publication

References 4 publications

Mpox virus Clade IIb detection in the air

Mpox virus Clade IIb detection in the air

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