Urinary-derived extracellular vesicle microRNAs as non‐invasive diagnostic biomarkers for early-stage renal cell carcinoma

Zhang, Yu; Zhu, Yuan-Yuan; Chen, Yang; Zhang, Lele; Wang, Rong; Ding, Xiaoyu; Zhang, Huizi; Zhang, Chen-Yu; Zhang, Chunni; Gu, Wan-Jian; Wang, Cheng; Wang, Jun-Jun

doi:10.1016/j.cca.2023.117672

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2024

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“…Nearly 60% of human protein-coding gene expression is regulated by miRNAs, therefore miRNAs were also regarded as of great importance in the development of tumors and multiple biological processes, such as cell division, death, inflammation, and proliferation. 7 For instance, miR-135b-5p is aberrantly expression in renal cell carcinoma 8 and pancreatic cancer. 9 It is understood the mechanism of miR-135b-5p in CRC, so the new study shows that target miR-135b-5p are significant in CRC.…”

Section: Introductionmentioning

confidence: 99%