Urinary Estimation of Optimal Fluoride Dosage with Domestic Salt

Ericsson, Yngve

doi:10.3109/00016357109026321

Cited by 11 publications

(7 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Because of these difficulties, fluoride excretion is taken as a good indicator of fluoride intake in children and adults who are in fluoride balance [Murray, 1986;Newbrun, 1986]. For example, fluoride excretion studies have been used extensively to determine optimum levels of salt fluo ridation [Ericsson, 1971;Marthaler, 1983;Mcnghini et al, 1989]. Most of these studies have recorded fluoride con centration in urine (which is the most important vehicle for fluoride excretion) but few have recorded the volume of urine excreted over 24 h or urinary tluoride excretion during 24 h. This is partly due to the technical difficulties of obtaining 24-hour urine collections from large numbers of volunteers and partly because a close positive correla tion between fluoride concentration in drinking water and fluoride concentration of spot samples of urine has been observed [McClure and Kinser, 1944], However, these lat-ter studies were conducted in adults who were generally well-nourished, living in temperate climates, before the widespread availability of fluoride toothpastes, and the correlations were closest in areas with water fluoride lev els over 1 ppmF [Myers.…”

mentioning

confidence: 99%

Urinary Fluoride Excretion in 4-Year-Old Children in Sri Lanka and England

Rugg-Gunn

Nunn²,

Ekanayake³

et al. 1993

Caries Res

View full text Add to dashboard Cite

Urine was collected over 24 h from children aged 4 years in Sri Lanka and England. Fifty-three children were from Dambulla, Sri Lanka, and 44 from Newcastle, England, both localities receiving drinking water containing 0.8–1.1 mg F/l. Urine volume was measured immediately after the 24-hour collection and samples of the collection from each child were frozen for transportation prior to ‘blind’ analysis in one laboratory for fluoride content. The mean 24-hour urine volumes were 504 ml (SD 198) in Sri Lanka and 449 ml (SD 196) in England (p = 0.17). The mean F concentrations were 1.19 ppm (SD0.63) in Sri Lanka and 1.02 ppm (SD 0.42) in England (p = 0.12). The mean weights of fluoride excreted were 0.55 mg F/day (SD 0.30) in Sri Lanka and 0.42 mgF/day (SD 0.19) in England (p = 0.009). The distributions of weight of fluoride excreted were also dissimilar in shape between the two countries. The extent to which these small differences in fluoride excretion in urine reflect differences in fluoride intake needs to be investigated.

show abstract

mentioning

confidence: 99%

Urinary Fluoride Excretion in 4-Year-Old Children in Sri Lanka and England

Rugg-Gunn

Nunn²,

Ekanayake³

et al. 1993

Caries Res

View full text Add to dashboard Cite

show abstract

“…MCGLURE & KINSER had found already in 1944 that within 24 h MCCLURE'S own urinaiy F closely approached that of the local drinking water when this was over 0.5 parts/lO^. In Uppsala, Sweden, with about 1.2 parts/106 p naturally occurring in the water, the 24-h urine of 8-to 19-year-old schoolchildren was found to contain an average of 0.8 parts/106 F (ERICSSON 1971).…”

Section: Discussionmentioning

confidence: 92%

“…PRODUCTION AND USE OF F-SALT F-salt was prepared in the laboratory by adding 500 mg F as NaF per kg ordinary domestic salt. The concentration was based on previous Swedish tests reported by ERICSSON (1971). Ten determinations on samples from different batches of the F-salt gave an average F concentration of 509 parts/10*^ with a standard deviation of 114 parts/10'*.…”

Section: Urinary F Excretion Course Following Single Dose F Supply Wimentioning

confidence: 99%

Urinary fluoride excretion in small children following short‐term fluoride supply with tablets or domestic salt

Hellström

Ericsson

1976

European J Oral Sciences

View full text Add to dashboard Cite

– Urinary fluoride (F) excretion has been studied in small children, with some comparisons with adults, following ingestion of F tablets or fluoridated salt (F‐salt) containing 500 mg F/kg NaCl. 24‐h urinary F in 7‐ to 8‐year‐old children in an institution and in 2‐ to 12‐year‐old children in families rapidly increased to average levels of about 0.85 and 0.55 parts/106, respectively, when the children had their meals spiced with F‐salt. Children in families also showed significantly elevated urinary F excretion with two F‐salted meals a day but not with one a day. After taking 0.5 mg F in the form of NaF tablets a group of children without previous F supply attained within 1 d a 24‐h urinary F concentration which was about the same as that in children who had been taking caries‐preventive tablet doses for years. The percentage of a single F dose excreted in the urine within 4 h after the ingestion of F tablets or an F‐salted standard meal was about the same in preschool children and middle‐aged adults. F quantities of the order 1.5–2 mg could be ingested by a child eating a meal comprising strongly F‐salted dishes, and the urine could reach concentrations around 3 parts/106 F during the following 2–4 h. The results obtained support the concept that domestic salt containing about 500 parts/106 F is suitable for clinical testing on a larger scale under Swedish conditions. Calculations of F supplies to children aged 2 months‐7 years with different diets and water and salt F contents are presented as digrams.

show abstract

“…These dishes were selected because they can be strongly salted, they are easy to homogenize, and they are liked by children also. The salt used for preparing these dishes was made to contain 500 ppm F, which had previously been found to give about the same urinary F excretion as F water, under common Swed ish dietary conditions [Ericsson, 1971]. A fortnight la ter the same subjects consumed, on a fasting stom- ach, large m easured volum es o f F w ater co n ta in in g 1.18 ppm F, which is about optimal for caries preven tion under Swedish conditions.…”

Section: Determination O F Plasma F Elevations Following Strongly F-smentioning

confidence: 99%

“…The salt consumption and the resulting F supply has been stud ied in different countries by Velicangil and Demirhindi [1958], Santesson and Breide [1962], Ganzoni-Ziegler [1965], Vines [1971], and Toth and Sugar [1975], While such studies are difficult, the main results support the possibility of moderately dis persed F dosage with domestic salt. The urinary F excretion after consumption of food prepared with F salt has been studied by several authors and compared with the corresponding excretion in subjects con suming F water [Wespi and Biirgi, 1969Ericsson, 1971;Tóth and Su gar, 1976], This method is very convenient and sufficiently accurate for determining an F dosage with the salt which gives the same average F supply as F water. The ef fects of salt and different nutrients on F absorption were studied in the rat by Ericsson [1968].…”

mentioning

confidence: 99%

Fluoride Ingestion with Fluoridated Domestic Salt under Swedish Dietary Conditions

Ericsson

Andersson

1983

Caries Res

View full text Add to dashboard Cite

The investigation had the purpose of studying the fluoride (F) doses obtained with fluoridated salt (F salt) under Swedish dietary conditions. 46 families in rural and urban areas of central Sweden used F salt containing 380 mg F/kg for 1 week and kept records of the quantities of every F-salted food consumed by the children and one of the adults of each family. A sample of every F-salted food was analyzed, and the F dose obtained was calculated for every F-salted dish, meal, and day. The results are reported separately for 1- to 3-year-old and 4- to 12-year-old children and for adults. The number of F-salted meals per day tended to increase with age, but in all groups the incidence of one such meal per day was near 50%, that of two F-salted meals per day about 25%. Average daily doses were slightly above 0.5 mg F in the younger children, 0.75–1 mg in the older children and between 1 and 2 mg in the adults. Single meal doses exceeding 1 mg were rare and distributed on several individuals. The F supply was fairly evenly distributed among 14 main types of foods except bread. On small groups of adults and children the blood plasma F concentrations were studied after a heavily F-salted test meal and compared with the corresponding concentrations after drinking large volumes of fluoridated water. The plasma F elevations were about as high after F salt as after F water although the test doses of F were more than twice as high with the Fsalt.

show abstract

Urinary Estimation of Optimal Fluoride Dosage with Domestic Salt

Cited by 11 publications

References 11 publications

Urinary Fluoride Excretion in 4-Year-Old Children in Sri Lanka and England

Urinary Fluoride Excretion in 4-Year-Old Children in Sri Lanka and England

Urinary fluoride excretion in small children following short‐term fluoride supply with tablets or domestic salt

Fluoride Ingestion with Fluoridated Domestic Salt under Swedish Dietary Conditions

Contact Info

Product

Resources

About