Urinary glyphosate and AMPA levels in a cross-sectional study of postmenopausal women: Associations with organic eating behavior and dietary intake

Lucia, Rachel McFarland; Liao, Xiyue; Huang, Weilin; Forman, Danielle; Kim, Alexis; Ziogas, Argyrios; Norden-Krichmar, Trina M.; Goodman, Deborah; Alvarez, Andrea; Masunaka, Irene; Pathak, Khyatiben V.; McGilvrey, Marissa; Hegde, Apurva M.; Pirrotte, Patrick; Park, Hannah Lui

doi:10.1016/j.ijheh.2023.114211

Cited by 3 publications

(1 citation statement)

References 71 publications

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“…A study evaluating glyphosate levels and their association with food consumption [ 117 ] identified glyphosate residues in 89.9% of urine samples and AMPA residues in 67.2% of urine samples. These samples were analyzed using LC-MS/MS in a group of postmenopausal women.…”

Section: Evidence Concerning Human Contamination By Glyphosate and Ri...mentioning

confidence: 99%

Glyphosate as a Food Contaminant: Main Sources, Detection Levels, and Implications for Human and Public Health

de Morais Valentim,

Coradi,

Viana

et al. 2024

Foods

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Glyphosate is a broad-spectrum pesticide that has become the most widely used herbicide globally. However, concerns have risen regarding its potential health impacts due to food contamination. Studies have detected glyphosate in human blood and urine samples, indicating human exposure and its persistence in the organism. A growing body of literature has reported the health risks concerning glyphosate exposure, suggesting that the daily intake of contaminated food and water poses a public health concern. Furthermore, countries with high glyphosate usage and lenient regulations regarding food and water contamination may face more severe consequences. In this context, in this review, we examined the literature regarding food contamination by glyphosate, discussed its detection methods, and highlighted its risks to human health.

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Section: Evidence Concerning Human Contamination By Glyphosate and Ri...mentioning

confidence: 99%

Glyphosate as a Food Contaminant: Main Sources, Detection Levels, and Implications for Human and Public Health

de Morais Valentim,

Coradi,

Viana

et al. 2024

Foods

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show abstract

Gestational glyphosate exposure and early childhood neurodevelopment in a Puerto Rico birth cohort

Jenkins,

Meeker,

Zimmerman

et al. 2024

Environmental Research

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Potential Role of Glyphosate, Glyphosate-Based Herbicides, and AMPA in Breast Cancer Development: A Review of Human and Human Cell-Based Studies

Schluter,

Bariami,

Park

2024

IJERPH

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The potential connection between exposure to glyphosate and glyphosate-based herbicides (GBHs) and breast cancer risk is a topic of research that is rapidly gaining the public’s attention due to the conflicting reports surrounding glyphosate’s potential carcinogenicity. In this review, we synthesize the current published biomedical literature works that have explored associations of glyphosate, its metabolite, aminomethylphosphonic acid (AMPA), and GBHs with breast cancer risk in humans and human cell-based models. Using PubMed as our search engine, we identified a total of 14 articles that were included in this review. In the four human studies, urinary glyphosate and/or AMPA were associated with breast cancer risk, endocrine disruption, oxidative stress biomarkers, and changes in DNA methylation patterns. Among most of the 10 human cell-based studies, glyphosate exhibited endocrine disruption, induced altered gene expression, increased DNA damage, and altered cell viability, while GBHs were more cytotoxic than glyphosate alone. In summary, numerous studies have shown glyphosate, AMPA, and GBHs to have potential carcinogenic, cytotoxic, or endocrine-disruptive properties. However, more human studies need to be conducted in order for more definitive and supported conclusions to be made on their potential effects on breast cancer risk.

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Urinary glyphosate and AMPA levels in a cross-sectional study of postmenopausal women: Associations with organic eating behavior and dietary intake

Cited by 3 publications

References 71 publications

Glyphosate as a Food Contaminant: Main Sources, Detection Levels, and Implications for Human and Public Health

Glyphosate as a Food Contaminant: Main Sources, Detection Levels, and Implications for Human and Public Health

Gestational glyphosate exposure and early childhood neurodevelopment in a Puerto Rico birth cohort

Potential Role of Glyphosate, Glyphosate-Based Herbicides, and AMPA in Breast Cancer Development: A Review of Human and Human Cell-Based Studies

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